@prefix this: . @prefix rdfs: . @prefix xsd: . @prefix sio: . @prefix ncit: . @prefix lld: . @prefix miriam-gene: . @prefix miriam-pubmed: . @prefix eco: . @prefix wi: . @prefix prov: . @prefix pav: . @prefix prv: . @prefix dcterms: . @prefix np: . @prefix dgn-np: . @prefix dgn-gda: . @prefix dgn-void: . dgn-np:NP940674.RA2ZXhtJIP2Rxuk_9qO7N-3QMOgnUsLz_gukqiiy8p6UQ130_head { this: np:hasAssertion dgn-np:NP940674.RA2ZXhtJIP2Rxuk_9qO7N-3QMOgnUsLz_gukqiiy8p6UQ130_assertion; np:hasProvenance dgn-np:NP940674.RA2ZXhtJIP2Rxuk_9qO7N-3QMOgnUsLz_gukqiiy8p6UQ130_provenance; np:hasPublicationInfo dgn-np:NP940674.RA2ZXhtJIP2Rxuk_9qO7N-3QMOgnUsLz_gukqiiy8p6UQ130_publicationInfo; a np:Nanopublication . dgn-np:NP940674.RA2ZXhtJIP2Rxuk_9qO7N-3QMOgnUsLz_gukqiiy8p6UQ130_assertion a np:Assertion . dgn-np:NP940674.RA2ZXhtJIP2Rxuk_9qO7N-3QMOgnUsLz_gukqiiy8p6UQ130_provenance a np:Provenance . dgn-np:NP940674.RA2ZXhtJIP2Rxuk_9qO7N-3QMOgnUsLz_gukqiiy8p6UQ130_publicationInfo a np:PublicationInfo . } dgn-np:NP940674.RA2ZXhtJIP2Rxuk_9qO7N-3QMOgnUsLz_gukqiiy8p6UQ130_assertion { miriam-gene:65057 a ncit:C16612 . lld:C0019693 a ncit:C7057 . dgn-gda:DGN87ae0d90e09ba014abd12f8a749e4ea3 sio:SIO_000628 miriam-gene:65057, lld:C0019693; a sio:SIO_001121 . } dgn-np:NP940674.RA2ZXhtJIP2Rxuk_9qO7N-3QMOgnUsLz_gukqiiy8p6UQ130_provenance { dgn-np:NP940674.RA2ZXhtJIP2Rxuk_9qO7N-3QMOgnUsLz_gukqiiy8p6UQ130_assertion dcterms:description "[To investigate the molecular mechanisms underlying the premature senescence of HIV-1-specific T cells, we focused here on the expression and function of a group of six nucleoproteins that are responsible for protecting and maintaining the structural integrity of telomeric DNA and are commonly referred to as 'shelterin.' We show that in progressive HIV-1 infection, the two major shelterin components TRF2 and TPP1 are selectively reduced in HIV-1-specific CD8 T cells, but not in T cells recognizing alternative viral species.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en; wi:evidence dgn-void:source_evidence_literature; sio:SIO_000772 miriam-pubmed:22398292; prov:wasDerivedFrom dgn-void:befree-20150227; prov:wasGeneratedBy eco:ECO_0000203 . dgn-void:befree-20150227 pav:importedOn "2015-02-27"^^xsd:date . dgn-void:source_evidence_literature a eco:ECO_0000212; rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en; rdfs:label "DisGeNET evidence - LITERATURE"@en . } dgn-np:NP940674.RA2ZXhtJIP2Rxuk_9qO7N-3QMOgnUsLz_gukqiiy8p6UQ130_publicationInfo { this: dcterms:created "2015-08-25T14:47:14+02:00"^^xsd:dateTime; dcterms:rights ; dcterms:rightsHolder dgn-void:IBIGroup; dcterms:subject sio:SIO_000983; prv:usedData dgn-void:disgenetv3.0rdf; pav:authoredBy , , , , ; pav:createdBy ; pav:version "v3.0.0.0" . dgn-void:disgenetv3.0rdf pav:version "v3.0.0" . }