sub:assertion {
d:DB00641 dv:ddi-interactor-in dr:DB00641_DB04855 .
d:DB04855 dv:ddi-interactor-in dr:DB00641_DB04855 .
dr:DB00641_DB04855 dct:identifier "drugbank_resource:DB00641_DB04855" ;
dct:title "DDI between Simvastatin and Dronedarone - Dronedarone is a CYP2D6 inhibitor thus increasing serum concentrations of simvastatin 4-fold. Lower doses of simvastatin and doses should not exceed 20 mg to avoid statin-induced toxicities like myopathy. Consider rosuvastatin as cholesterol lowering therapy as there is no significant interaction between rosuvastatin and dronedarone."@en ;
a dv:Drug-Drug-Interaction ;
rdfs:label "DDI between Simvastatin and Dronedarone - Dronedarone is a CYP2D6 inhibitor thus increasing serum concentrations of simvastatin 4-fold. Lower doses of simvastatin and doses should not exceed 20 mg to avoid statin-induced toxicities like myopathy. Consider rosuvastatin as cholesterol lowering therapy as there is no significant interaction between rosuvastatin and dronedarone. [drugbank_resource:DB00641_DB04855]"@en .
}