@prefix this: . @prefix rdfs: . @prefix xsd: . @prefix sio: . @prefix ncit: . @prefix lld: . @prefix miriam-gene: . @prefix miriam-pubmed: . @prefix eco: . @prefix wi: . @prefix prov: . @prefix pav: . @prefix prv: . @prefix dcterms: . @prefix np: . @prefix dgn-np: . @prefix dgn-gda: . @prefix dgn-void: . dgn-np:NP48689.RA28fAS7GXMrpYjYytAixKcoifgLLmrjEt4KFzKMcxVBk130_head { this: np:hasAssertion dgn-np:NP48689.RA28fAS7GXMrpYjYytAixKcoifgLLmrjEt4KFzKMcxVBk130_assertion; np:hasProvenance dgn-np:NP48689.RA28fAS7GXMrpYjYytAixKcoifgLLmrjEt4KFzKMcxVBk130_provenance; np:hasPublicationInfo dgn-np:NP48689.RA28fAS7GXMrpYjYytAixKcoifgLLmrjEt4KFzKMcxVBk130_publicationInfo; a np:Nanopublication . dgn-np:NP48689.RA28fAS7GXMrpYjYytAixKcoifgLLmrjEt4KFzKMcxVBk130_assertion a np:Assertion . dgn-np:NP48689.RA28fAS7GXMrpYjYytAixKcoifgLLmrjEt4KFzKMcxVBk130_provenance a np:Provenance . dgn-np:NP48689.RA28fAS7GXMrpYjYytAixKcoifgLLmrjEt4KFzKMcxVBk130_publicationInfo a np:PublicationInfo . } dgn-np:NP48689.RA28fAS7GXMrpYjYytAixKcoifgLLmrjEt4KFzKMcxVBk130_assertion { miriam-gene:6775 a ncit:C16612 . lld:C0004096 a ncit:C7057 . dgn-gda:DGNd14dbb744347da5a1278d82056d31bf1 sio:SIO_000628 miriam-gene:6775, lld:C0004096; a sio:SIO_001120 . } dgn-np:NP48689.RA28fAS7GXMrpYjYytAixKcoifgLLmrjEt4KFzKMcxVBk130_provenance { dgn-np:NP48689.RA28fAS7GXMrpYjYytAixKcoifgLLmrjEt4KFzKMcxVBk130_assertion dcterms:description "[20 +/- 1.75)% were all significantly higher than those of the control group (1.51 +/- 1.04) x 10(7)/L, (0.70 +/- 0.48)% (P < 0.01); the total cell numbers in BALF, the absolute numbers of EOS and EOS% of RA groups (14.89 +/- 2.35) x 10(7)/L, (4.70 +/- 0.82)%; (10.98 +/- 1.81) x 10(7)/L, (3.56 +/- 0.53)% were all significantly lower than those of asthma group (P < 0.01); (2) The concentration of IL-4 in BALF of asthma group (25.70 +/- 7.36) was significantly higher than that of the control group (8.55 +/- 2.97) (P < 0.01); the concentration of IL-4 of BALF of RA groups (31.89 +/- 5.46), (35.26 +/- 6.03) was significantly lower than that of asthma group (P < 0.01); the concentration of IL-12 of BALF of asthma group (16.10 +/- 3.38) was significantly lower than that of the control group (42.33 +/- 9.66) (P < 0.01); the concentration of IL-12 of BALF of the RA groups (31.89 +/- 5.46), (35.26 +/- 6.03) was significantly higher than that of the asthma group (P < 0.01); (3) Immunohistochemistry and in situ hybridization showed that the protein content of STAT4 and the STAT4 mRNA expression around the bronchus of asthma group (0.096 +/- 0.012), (0.098 +/- 0.011) were lower than those of the control group (0.216 +/- 0.034), (0.228 +/- 0.032), while those of RA groups (0.176 +/- 0.012), (0.185 +/- 0.023); (0.183 +/- 0.011), (0.201 +/- 0.019) were all significantly higher than that of the asthma group (P < 0.01), the airway smooth muscle cells, the pulmonary arterial smooth muscle cells and endothelial cells were the chief expression cells; (4) the STAT4 and the STAT4mRNA expression around the bronchus had positive correlation with the concentration of IL-12 in BALF while had negative correlation with the concentration of IL-4, absolute numbers of EOS in BALF.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en; wi:evidence dgn-void:source_evidence_predicted; sio:SIO_000772 miriam-pubmed:18211752; prov:wasDerivedFrom dgn-void:rgd-20150221; prov:wasGeneratedBy eco:ECO_0000218 . dgn-void:rgd-20150221 pav:importedOn "2015-02-21"^^xsd:date . dgn-void:source_evidence_predicted a eco:ECO_0000266; rdfs:comment "Gene-disease associations inferred from animal model manually asserted gene-disease associations."@en; rdfs:label "DisGeNET evidence - PREDICTED"@en . } dgn-np:NP48689.RA28fAS7GXMrpYjYytAixKcoifgLLmrjEt4KFzKMcxVBk130_publicationInfo { this: dcterms:created "2015-08-25T14:38:06+02:00"^^xsd:dateTime; dcterms:rights ; dcterms:rightsHolder dgn-void:IBIGroup; dcterms:subject sio:SIO_000983; prv:usedData dgn-void:disgenetv3.0rdf; pav:authoredBy , , , , ; pav:createdBy ; pav:version "v3.0.0.0" . dgn-void:disgenetv3.0rdf pav:version "v3.0.0" . }