dgn-np:NP48689.RA28fAS7GXMrpYjYytAixKcoifgLLmrjEt4KFzKMcxVBk130_provenance {
  dgn-np:NP48689.RA28fAS7GXMrpYjYytAixKcoifgLLmrjEt4KFzKMcxVBk130_assertion dcterms:description "[20 +/- 1.75)% were all significantly higher than those of the control group (1.51 +/- 1.04) x 10(7)/L, (0.70 +/- 0.48)% (P < 0.01); the total cell numbers in BALF, the absolute numbers of EOS and EOS% of RA groups (14.89 +/- 2.35) x 10(7)/L, (4.70 +/- 0.82)%; (10.98 +/- 1.81) x 10(7)/L, (3.56 +/- 0.53)% were all significantly lower than those of asthma group (P < 0.01); (2) The concentration of IL-4 in BALF of asthma group (25.70 +/- 7.36) was significantly higher than that of the control group (8.55 +/- 2.97) (P < 0.01); the concentration of IL-4 of BALF of RA groups (31.89 +/- 5.46), (35.26 +/- 6.03) was significantly lower than that of asthma group (P < 0.01); the concentration of IL-12 of BALF of asthma group (16.10 +/- 3.38) was significantly lower than that of the control group (42.33 +/- 9.66) (P < 0.01); the concentration of IL-12 of BALF of the RA groups (31.89 +/- 5.46), (35.26 +/- 6.03) was significantly higher than that of the asthma group (P < 0.01); (3) Immunohistochemistry and in situ hybridization showed that the protein content of STAT4 and the STAT4 mRNA expression around the bronchus of asthma group (0.096 +/- 0.012), (0.098 +/- 0.011) were lower than those of the control group (0.216 +/- 0.034), (0.228 +/- 0.032), while those of RA groups (0.176 +/- 0.012), (0.185 +/- 0.023); (0.183 +/- 0.011), (0.201 +/- 0.019) were all significantly higher than that of the asthma group (P < 0.01), the airway smooth muscle cells, the pulmonary arterial smooth muscle cells and endothelial cells were the chief expression cells; (4) the STAT4 and the STAT4mRNA expression around the bronchus had positive correlation with the concentration of IL-12 in BALF while had negative correlation with the concentration of IL-4, absolute numbers of EOS in BALF.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en ;
    wi:evidence dgn-void:source_evidence_predicted ;
    sio:SIO_000772 miriam-pubmed:18211752 ;
    prov:wasDerivedFrom dgn-void:rgd-20150221 ;
    prov:wasGeneratedBy eco:ECO_0000218 .
  dgn-void:rgd-20150221 pav:importedOn "2015-02-21"^^xsd:date .
  dgn-void:source_evidence_predicted a eco:ECO_0000266 ;
    rdfs:comment "Gene-disease associations inferred from animal model manually asserted gene-disease associations."@en ;
    rdfs:label "DisGeNET evidence - PREDICTED"@en .
}