@prefix dcterms: .
@prefix this: .
@prefix sub: .
@prefix beldoc: .
@prefix rdfs: .
@prefix rdf: .
@prefix xsd: .
@prefix dce: .
@prefix pav: .
@prefix np: .
@prefix belv: .
@prefix prov: .
@prefix schem: .
@prefix RNA: .
@prefix hgnc: .
@prefix geneProductOf: .
@prefix species: .
@prefix occursIn: .
@prefix mesh: .
@prefix atcc: .
@prefix pubmed: .
@prefix orcid: .
sub:Head {
this: np:hasAssertion sub:assertion;
np:hasProvenance sub:provenance;
np:hasPublicationInfo sub:pubinfo;
a np:Nanopublication .
}
sub:assertion {
sub:_1 geneProductOf: hgnc:21391;
a RNA: .
sub:_2 occursIn: mesh:D008264, atcc:CRL-1593.2.aspx, species:9606;
rdf:object sub:_1;
rdf:predicate belv:decreases;
rdf:subject schem:Low%20Density%20Lipoprotein;
a rdf:Statement .
sub:assertion rdfs:label "a(SCHEM:\"Low Density Lipoprotein\") -| r(HGNC:SLAMF8)" .
}
sub:provenance {
beldoc: dce:description "Approximately 61,000 statements.";
dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved.";
dce:title "BEL Framework Large Corpus Document";
pav:authoredBy sub:_4;
pav:version "1.4" .
sub:_3 prov:value "Table 4 Relative expression (RE) of 29 selected cellular genes in four study models by real-time RT-PCR - see comparisons below: Model 2 (M2) values were normalized against the untreated control macrophages of model 1 (M1) at 24 h. Model 3 (M3) values were normalized against M1 at 72 h. Models 4 and 5 (M4 and M5) were normalized against M1 at 96 h. M1@24, M1@72 and M1@96 denote control untreated macrophages whose RNAs were harvested and analyzed at 24, 72 and 96 h, respectively. M2@24 denotes LDL-treated macrophages with RNA analyzed at 24 h. M3@72 denotes macrophages infected with C. pneumoniae and RNA analyzed at 72 h. M4@96 denotes macrophages treated with LDL for 24 h, followed by C. pneumoniae infection for another 72 h before analyzing RNA at 96 h. M5@96 denotes macrophages infected with C. pneumoniae first for 72 h, followed by LDL treatment for another 24 h before analyzing RNA at 96 h. {for M4 and M5, results were combined and only the overlapping gene changes were modeled} (from methods) The two-tailed t-test was then conducted to ascertain the statistical significance of the differences between the normalized relative expression values for each gene under the conditions stipulated for study models 2, 3, 4 and 5";
prov:wasQuotedFrom pubmed:16466844 .
sub:_4 rdfs:label "Selventa" .
sub:assertion prov:hadPrimarySource pubmed:16466844;
prov:wasDerivedFrom beldoc:, sub:_3 .
}
sub:pubinfo {
this: dcterms:created "2014-07-03T14:30:41.483+02:00"^^xsd:dateTime;
pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 .
}