@prefix this: . @prefix rdfs: . @prefix xsd: . @prefix sio: . @prefix ncit: . @prefix lld: . @prefix miriam-gene: . @prefix miriam-pubmed: . @prefix eco: . @prefix wi: . @prefix prov: . @prefix pav: . @prefix prv: . @prefix dcterms: . @prefix np: . @prefix dgn-np: . @prefix dgn-gda: . @prefix dgn-void: . dgn-np:NP420886.RA1egi_JZCkzUH7131oJixtlWwADjN0Rf-Gu1N6BeQdrs130_head { this: np:hasAssertion dgn-np:NP420886.RA1egi_JZCkzUH7131oJixtlWwADjN0Rf-Gu1N6BeQdrs130_assertion; np:hasProvenance dgn-np:NP420886.RA1egi_JZCkzUH7131oJixtlWwADjN0Rf-Gu1N6BeQdrs130_provenance; np:hasPublicationInfo dgn-np:NP420886.RA1egi_JZCkzUH7131oJixtlWwADjN0Rf-Gu1N6BeQdrs130_publicationInfo; a np:Nanopublication . dgn-np:NP420886.RA1egi_JZCkzUH7131oJixtlWwADjN0Rf-Gu1N6BeQdrs130_assertion a np:Assertion . dgn-np:NP420886.RA1egi_JZCkzUH7131oJixtlWwADjN0Rf-Gu1N6BeQdrs130_provenance a np:Provenance . dgn-np:NP420886.RA1egi_JZCkzUH7131oJixtlWwADjN0Rf-Gu1N6BeQdrs130_publicationInfo a np:PublicationInfo . } dgn-np:NP420886.RA1egi_JZCkzUH7131oJixtlWwADjN0Rf-Gu1N6BeQdrs130_assertion { miriam-gene:1131 a ncit:C16612 . lld:C1868682 a ncit:C7057 . dgn-gda:DGN4407860b5dc54878de7a64faebee5c7f sio:SIO_000628 miriam-gene:1131, lld:C1868682; a sio:SIO_001121 . } dgn-np:NP420886.RA1egi_JZCkzUH7131oJixtlWwADjN0Rf-Gu1N6BeQdrs130_provenance { dgn-np:NP420886.RA1egi_JZCkzUH7131oJixtlWwADjN0Rf-Gu1N6BeQdrs130_assertion dcterms:description "[The results indicate that: (a) the expression of the human NPY gene in SH-SY5Y cells is stimulated by the cholinergic muscarinic agonist, carbachol; (b) this effect is mediated by the M3 muscarinic receptor subtype, as indicated by the inhibitory effect of the M3 antagonist 4-DAMP; (c) protein kinase C (PKC) activation plays an important role in the induction of NPY gene expression in this system, as suggested by experiments with the PKC activator, TPA, and the PKC inhibitor, GF 109203X; (d) the stimulation of NPY mRNA levels by TPA and by carbachol in SH-SY5Y cells requires de novo synthesis of RNA and protein.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en; wi:evidence dgn-void:source_evidence_literature; sio:SIO_000772 miriam-pubmed:9666082; prov:wasDerivedFrom dgn-void:befree-20140225; prov:wasGeneratedBy eco:ECO_0000203 . dgn-void:befree-20140225 pav:importedOn "2014-02-25"^^xsd:date . dgn-void:source_evidence_literature a eco:ECO_0000212; rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en; rdfs:label "DisGeNET evidence - LITERATURE"@en . } dgn-np:NP420886.RA1egi_JZCkzUH7131oJixtlWwADjN0Rf-Gu1N6BeQdrs130_publicationInfo { this: dcterms:created "2014-10-02T12:36:09+02:00"^^xsd:dateTime; dcterms:rights ; dcterms:rightsHolder dgn-void:IBIGroup; dcterms:subject sio:SIO_000983; prv:usedData dgn-void:disgenetrdf; pav:authoredBy , , , , ; pav:createdBy ; pav:version "v2.1.0.0" . dgn-void:disgenetrdf pav:version "v2.1.0" . }