@prefix this: <http://bio2rdf.org/drugbank:DB00398_nanopub.RA1P0MjptLGunlhkR8P7uUrqoUK48ws5X3oZXXkKWNx4o> .
@prefix sub: <http://bio2rdf.org/drugbank:DB00398_nanopub.RA1P0MjptLGunlhkR8P7uUrqoUK48ws5X3oZXXkKWNx4o#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix pav: <http://purl.org/pav/> .
@prefix orcid: <http://orcid.org/> .
@prefix codebase: <https://github.com/tkuhn/bio2rdf2nanopub> .
@prefix version: <https://github.com/tkuhn/bio2rdf2nanopub/tree/eda7951a5f6c622c5d2132f50c3093138484a349> .
@prefix instance: <https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB> .
@prefix process: <https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB.7720f136-841b-4851-a6e4-ad20a409a475> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix v: <http://bio2rdf.org/bio2rdf_vocabulary:> .
@prefix d: <http://bio2rdf.org/drugbank:> .
@prefix dv: <http://bio2rdf.org/drugbank_vocabulary:> .
@prefix dr: <http://bio2rdf.org/drugbank_resource:> .
@prefix dcat: <http://www.w3.org/ns/dcat#> .
@prefix npx: <http://purl.org/nanopub/x/> .

sub:head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:publicationInfo;
    a np:Nanopublication .
}

sub:assertion {
  d:DB00398 v:identifier "DB00398";
    v:namespace "drugbank";
    v:uri "http://bio2rdf.org/drugbank:DB00398";
    v:x-identifiers.org <http://identifiers.org/drugbank/DB00398>;
    dv:drugbank-id "APRD01304", "DB00398", "DB07438";
    dv:x-ahfs <http://bio2rdf.org/ahfs:92:00.00>;
    dv:x-atc <http://bio2rdf.org/atc:L01XE05>;
    dv:x-bindingdb <http://bio2rdf.org/bindingdb:16673>;
    dv:x-cas <http://bio2rdf.org/cas:284461-73-0>;
    dv:x-chebi <http://bio2rdf.org/chebi:50924>;
    dv:x-chemspider <http://bio2rdf.org/chemspider:187440>;
    dv:x-kegg <http://bio2rdf.org/kegg:D08524>;
    dv:x-ndc <http://bio2rdf.org/ndc:50419-488-58>;
    dv:x-pdb <http://bio2rdf.org/pdb:BAX>;
    dv:x-pharmgkb <http://bio2rdf.org/pharmgkb:PA7000>;
    dv:x-pubchemcompound <http://bio2rdf.org/pubchem.compound:216239>;
    dv:x-pubchemsubstance <http://bio2rdf.org/pubchem.substance:46505329>;
    dv:x-wikipedia <http://bio2rdf.org/wikipedia:Sorafenib>;
    dct:description """Sorafenib (rINN), marketed as Nexavar by Bayer, is a drug approved for the treatment of advanced renal cell carcinoma (primary kidney cancer). It has also received \"Fast Track\" designation by the FDA for the treatment of advanced hepatocellular carcinoma (primary liver cancer), and has since performed well in Phase III trials.
Sorafenib is a small molecular inhibitor of Raf kinase, PDGF (platelet-derived growth factor), VEGF receptor 2 & 3 kinases and c Kit the receptor for Stem cell factor. A growing number of drugs target most of these pathways. The originality of Sorafenib lays in its simultaneous targeting of the Raf/Mek/Erk pathway."""@en;
    dct:identifier "drugbank:DB00398";
    dct:title "Sorafenib"@en;
    a dv:Drug;
    rdfs:label "Sorafenib [drugbank:DB00398]"@en;
    rdfs:seeAlso <http://www.drugbank.ca/drugs/DB00398>, <http://www.drugs.com/cdi/sorafenib.html>,
      <http://www.rxlist.com/nexavar-drug.htm> .
}

sub:provenance {
  sub:assertion prov:wasDerivedFrom <http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz> .
  
  dr:bio2rdf.dataset.drugbank.R3 dcat:distribution <http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz> .
  
  <http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz> dct:created "2015-01-09T17:00:50-05:00"^^xsd:dateTime;
    prov:wasDerivedFrom <http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip#retrieved-on:2014-11-12T07:57:03-05:00> .
  
  <http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip#retrieved-on:2014-11-12T07:57:03-05:00>
    pav:retrievedOn "2014-11-12T07:57:03-05:00"^^xsd:dateTime;
    prov:wasDerivedFrom <http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip> .
  
  <http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip> prov:wasAttributedTo
      <http://drugbank.ca> .
}

sub:publicationInfo {
  sub:signature.MCwCFCfNzsvCP35N npx:hasPublicKey "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";
    npx:hasSignature "MCwCFCfNzsvCP35NDarx7rDx2+77pKvuAhQ4mn5W1qkciK7Nu/vYWvcpcin1Vw==";
    npx:signedBy instance: .
  
  this: dct:created "2018-03-30T11:10:35.060+02:00"^^xsd:dateTime;
    dct:license <https://creativecommons.org/licenses/by-nc/4.0/>;
    npx:hasSignatureElement sub:signature.MCwCFCfNzsvCP35N;
    prov:wasGeneratedBy process: .
  
  instance: prov:specializationOf codebase:;
    prov:wasAttributedTo orcid:0000-0002-1267-0234 .
  
  process: dct:identifier "7720f136-841b-4851-a6e4-ad20a409a475";
    prov:used version:;
    prov:wasAssociatedWith instance:;
    prov:wasStartedBy orcid:0000-0002-1267-0234 .
  
  version: dct:isVersionOf codebase:;
    pav:version "eda7951a5f6c622c5d2132f50c3093138484a349";
    prov:wasAttributedTo orcid:0000-0002-1267-0234 .
}