. . . . . . . . . . . . . . "cat(p(MGI:Cyb5r4)) -| a(SCHEM:\"serum glucose\")" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "1.4" . "At 4 weeks of age, in the fed state, Ncb5or -/- mice had normal blood glucose levels (Fig. 2a) but insulin levels were 40% those of wild-type littermates (Fig. 2b). These animals had impaired tolerance to an i.p. injection of glucose (Fig. 2c), suggesting decreased insulin reserve, i.e., prediabetes. By 7 weeks of age, the blood glucose levels in Ncb5or -/- mice were 3-fold higher than those in +/+ mice during the fed state or after an overnight fast (Fig. 2a). The hyperglycemia in the Ncb5or -/- animals was associated with a marked reduction in plasma insulin. In the fed state, insulin levels of 7-week-old Ncb5or -/- animals were decreased to 25% of the levels in normal animals (Fig. 2b). Insulin was barely detectable in the plasma of fasting Ncb5or -/- animals (data not shown). These data indicate that, between 4 and 7 weeks of age, there was a progressive deterioration of glucose homeostasis in Ncb5or -/- mice." . . "Selventa" . . . . "2014-07-03T14:30:25.814+02:00"^^ . . .