http://rdf.disgenet.org/nanopublications.trig#NP188677.RA17UFm7KQrAfWDtqPT1f8z3VkVJGYTGIx2uaTe94rE2A130_head http://rdf.disgenet.org/nanopublications.trig#NP188677.RA17UFm7KQrAfWDtqPT1f8z3VkVJGYTGIx2uaTe94rE2A http://www.nanopub.org/nschema#hasAssertion http://rdf.disgenet.org/nanopublications.trig#NP188677.RA17UFm7KQrAfWDtqPT1f8z3VkVJGYTGIx2uaTe94rE2A130_assertion http://rdf.disgenet.org/nanopublications.trig#NP188677.RA17UFm7KQrAfWDtqPT1f8z3VkVJGYTGIx2uaTe94rE2A http://www.nanopub.org/nschema#hasProvenance http://rdf.disgenet.org/nanopublications.trig#NP188677.RA17UFm7KQrAfWDtqPT1f8z3VkVJGYTGIx2uaTe94rE2A130_provenance http://rdf.disgenet.org/nanopublications.trig#NP188677.RA17UFm7KQrAfWDtqPT1f8z3VkVJGYTGIx2uaTe94rE2A http://www.nanopub.org/nschema#hasPublicationInfo http://rdf.disgenet.org/nanopublications.trig#NP188677.RA17UFm7KQrAfWDtqPT1f8z3VkVJGYTGIx2uaTe94rE2A130_publicationInfo http://rdf.disgenet.org/nanopublications.trig#NP188677.RA17UFm7KQrAfWDtqPT1f8z3VkVJGYTGIx2uaTe94rE2A http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://rdf.disgenet.org/nanopublications.trig#NP188677.RA17UFm7KQrAfWDtqPT1f8z3VkVJGYTGIx2uaTe94rE2A130_assertion http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Assertion http://rdf.disgenet.org/nanopublications.trig#NP188677.RA17UFm7KQrAfWDtqPT1f8z3VkVJGYTGIx2uaTe94rE2A130_provenance http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Provenance http://rdf.disgenet.org/nanopublications.trig#NP188677.RA17UFm7KQrAfWDtqPT1f8z3VkVJGYTGIx2uaTe94rE2A130_publicationInfo http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#PublicationInfo http://rdf.disgenet.org/nanopublications.trig#NP188677.RA17UFm7KQrAfWDtqPT1f8z3VkVJGYTGIx2uaTe94rE2A130_assertion http://identifiers.org/ncbigene/9372 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16612 http://linkedlifedata.com/resource/umls/id/C0021400 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7057 http://rdf.disgenet.org/gene-disease-association.ttl#DGNe8a3e21171a85cd1d46c1471978bec7c http://semanticscience.org/resource/SIO_000628 http://identifiers.org/ncbigene/9372 http://rdf.disgenet.org/gene-disease-association.ttl#DGNe8a3e21171a85cd1d46c1471978bec7c http://semanticscience.org/resource/SIO_000628 http://linkedlifedata.com/resource/umls/id/C0021400 http://rdf.disgenet.org/gene-disease-association.ttl#DGNe8a3e21171a85cd1d46c1471978bec7c http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://semanticscience.org/resource/SIO_001121 http://rdf.disgenet.org/nanopublications.trig#NP188677.RA17UFm7KQrAfWDtqPT1f8z3VkVJGYTGIx2uaTe94rE2A130_provenance http://rdf.disgenet.org/nanopublications.trig#NP188677.RA17UFm7KQrAfWDtqPT1f8z3VkVJGYTGIx2uaTe94rE2A130_assertion http://purl.org/dc/terms/description [The following observations were made: (i) recent isolates showed an about 2-fold increase in the number of glycosylation sites of HA and NA when compared to isolates from 1968 to 1970; (ii) during passages of clinical strains in CACO-2 and MDCK cells HA and NA mutated cooperatively with strain-specific variations implying that functioning of the HA-NA complex varied from strain to strain in one influenza outbreak; (iii) there were no amino acid exchanges in the HA receptor binding site although the viruses acquired the ability to agglutinate avian erythrocytes after passage in MDCK cells, suggesting that virus adsorption is regulated by several factors; (iv) quasispecies characterized by deletion of 66 nucleotides (22 amino acids) in the stalk region of the NA gene was dominant in naso-pharyngeal washes of all patients whereas during passaging in CACO-2 cells this deleted genotype in isolates from different patients was either stably retained as prevalent quasispecies or rapidly replaced for that one containing full length NA gene; (v) the M2 protein of clinical viruses was sensitive to amantadine; (vi) the NS segment of human viruses, unlike the most of avian ones, contained an additional positive-sense open reading frame encoding a hypothetical 25kD polypeptide (negative strand protein, NSP).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine. http://rdf.disgenet.org/nanopublications.trig#NP188677.RA17UFm7KQrAfWDtqPT1f8z3VkVJGYTGIx2uaTe94rE2A130_assertion http://purl.org/ontology/wi/core#evidence http://rdf.disgenet.org/v2.1.0/void.ttl#source_evidence_literature http://rdf.disgenet.org/nanopublications.trig#NP188677.RA17UFm7KQrAfWDtqPT1f8z3VkVJGYTGIx2uaTe94rE2A130_assertion http://semanticscience.org/resource/SIO_000772 http://identifiers.org/pubmed/19546028 http://rdf.disgenet.org/nanopublications.trig#NP188677.RA17UFm7KQrAfWDtqPT1f8z3VkVJGYTGIx2uaTe94rE2A130_assertion http://www.w3.org/ns/prov#wasDerivedFrom http://rdf.disgenet.org/v2.1.0/void.ttl#befree-20140225 http://rdf.disgenet.org/nanopublications.trig#NP188677.RA17UFm7KQrAfWDtqPT1f8z3VkVJGYTGIx2uaTe94rE2A130_assertion http://www.w3.org/ns/prov#wasGeneratedBy http://purl.obolibrary.org/obo/eco.owl#ECO_0000203 http://rdf.disgenet.org/v2.1.0/void.ttl#befree-20140225 http://purl.org/pav/2.0/importedOn 2014-02-25 http://rdf.disgenet.org/v2.1.0/void.ttl#source_evidence_literature http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://purl.obolibrary.org/obo/eco.owl#ECO_0000212 http://rdf.disgenet.org/v2.1.0/void.ttl#source_evidence_literature http://www.w3.org/2000/01/rdf-schema#comment Gene-disease associations inferred from text-mining the literature. http://rdf.disgenet.org/v2.1.0/void.ttl#source_evidence_literature http://www.w3.org/2000/01/rdf-schema#label DisGeNET evidence - LITERATURE http://rdf.disgenet.org/nanopublications.trig#NP188677.RA17UFm7KQrAfWDtqPT1f8z3VkVJGYTGIx2uaTe94rE2A130_publicationInfo http://rdf.disgenet.org/nanopublications.trig#NP188677.RA17UFm7KQrAfWDtqPT1f8z3VkVJGYTGIx2uaTe94rE2A http://purl.org/dc/terms/created 2014-10-02T12:33:43+02:00 http://rdf.disgenet.org/nanopublications.trig#NP188677.RA17UFm7KQrAfWDtqPT1f8z3VkVJGYTGIx2uaTe94rE2A http://purl.org/dc/terms/rights http://opendatacommons.org/licenses/odbl/1.0/ http://rdf.disgenet.org/nanopublications.trig#NP188677.RA17UFm7KQrAfWDtqPT1f8z3VkVJGYTGIx2uaTe94rE2A http://purl.org/dc/terms/rightsHolder http://rdf.disgenet.org/v2.1.0/void.ttl#IBIGroup http://rdf.disgenet.org/nanopublications.trig#NP188677.RA17UFm7KQrAfWDtqPT1f8z3VkVJGYTGIx2uaTe94rE2A http://purl.org/dc/terms/subject http://semanticscience.org/resource/SIO_000983 http://rdf.disgenet.org/nanopublications.trig#NP188677.RA17UFm7KQrAfWDtqPT1f8z3VkVJGYTGIx2uaTe94rE2A http://purl.org/net/provenance/ns#usedData http://rdf.disgenet.org/v2.1.0/void.ttl#disgenetrdf http://rdf.disgenet.org/nanopublications.trig#NP188677.RA17UFm7KQrAfWDtqPT1f8z3VkVJGYTGIx2uaTe94rE2A http://purl.org/pav/2.0/authoredBy http://orcid.org/0000-0001-5999-6269 http://rdf.disgenet.org/nanopublications.trig#NP188677.RA17UFm7KQrAfWDtqPT1f8z3VkVJGYTGIx2uaTe94rE2A http://purl.org/pav/2.0/authoredBy http://orcid.org/0000-0002-7534-7661 http://rdf.disgenet.org/nanopublications.trig#NP188677.RA17UFm7KQrAfWDtqPT1f8z3VkVJGYTGIx2uaTe94rE2A http://purl.org/pav/2.0/authoredBy http://orcid.org/0000-0002-9383-528X http://rdf.disgenet.org/nanopublications.trig#NP188677.RA17UFm7KQrAfWDtqPT1f8z3VkVJGYTGIx2uaTe94rE2A http://purl.org/pav/2.0/authoredBy http://orcid.org/0000-0003-0169-8159 http://rdf.disgenet.org/nanopublications.trig#NP188677.RA17UFm7KQrAfWDtqPT1f8z3VkVJGYTGIx2uaTe94rE2A http://purl.org/pav/2.0/authoredBy http://orcid.org/0000-0003-1244-7654 http://rdf.disgenet.org/nanopublications.trig#NP188677.RA17UFm7KQrAfWDtqPT1f8z3VkVJGYTGIx2uaTe94rE2A http://purl.org/pav/2.0/createdBy http://orcid.org/0000-0003-0169-8159 http://rdf.disgenet.org/nanopublications.trig#NP188677.RA17UFm7KQrAfWDtqPT1f8z3VkVJGYTGIx2uaTe94rE2A http://purl.org/pav/2.0/version v2.1.0.0 http://rdf.disgenet.org/v2.1.0/void.ttl#disgenetrdf http://purl.org/pav/2.0/version v2.1.0