@prefix this: <
http://bio2rdf.org/drugbank:DB00024_nanopub.RA0xsrpNtO0dRiu5P8xC3EaWTh-0ywWmTFy0mlZAVNAcM
> .
@prefix sub: <
http://bio2rdf.org/drugbank:DB00024_nanopub.RA0xsrpNtO0dRiu5P8xC3EaWTh-0ywWmTFy0mlZAVNAcM#
> .
@prefix prov: <
http://www.w3.org/ns/prov#
> .
@prefix dct: <
http://purl.org/dc/terms/
> .
@prefix pav: <
http://purl.org/pav/
> .
@prefix orcid: <
http://orcid.org/
> .
@prefix codebase: <
https://github.com/tkuhn/bio2rdf2nanopub
> .
@prefix version: <
https://github.com/tkuhn/bio2rdf2nanopub/tree/eda7951a5f6c622c5d2132f50c3093138484a349
> .
@prefix instance: <
https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB
> .
@prefix process: <
https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB.7720f136-841b-4851-a6e4-ad20a409a475
> .
@prefix np: <
http://www.nanopub.org/nschema#
> .
@prefix rdfs: <
http://www.w3.org/2000/01/rdf-schema#
> .
@prefix xsd: <
http://www.w3.org/2001/XMLSchema#
> .
@prefix v: <
http://bio2rdf.org/bio2rdf_vocabulary:
> .
@prefix d: <
http://bio2rdf.org/drugbank:
> .
@prefix dv: <
http://bio2rdf.org/drugbank_vocabulary:
> .
@prefix dr: <
http://bio2rdf.org/drugbank_resource:
> .
@prefix dcat: <
http://www.w3.org/ns/dcat#
> .
@prefix npx: <
http://purl.org/nanopub/x/
> .
sub:head
{
this:
np:hasAssertion
sub:assertion
;
np:hasProvenance
sub:provenance
;
np:hasPublicationInfo
sub:publicationInfo
;
a
np:Nanopublication
.
}
sub:assertion
{
d:DB00024
v:identifier
"DB00024" ;
v:namespace
"drugbank" ;
v:uri
"http://bio2rdf.org/drugbank:DB00024" ;
v:x-identifiers.org
<
http://identifiers.org/drugbank/DB00024
> ;
dv:drugbank-id
"BIOD00020" , "BTD00020" , "DB00024" ;
dv:x-ahfs
<
http://bio2rdf.org/ahfs:36:60.00
> ;
dv:x-atc
<
http://bio2rdf.org/atc:V04CJ01
> ;
dv:x-cas
<
http://bio2rdf.org/cas:9002-71-5
> ;
dv:x-dpd
<
http://bio2rdf.org/dpd:2246016
> ;
dv:x-genbank
<
http://bio2rdf.org/genbank:M16647
> ;
dv:x-ndc
<
http://bio2rdf.org/ndc:58468-1849-4
> ;
dv:x-pharmgkb
<
http://bio2rdf.org/pharmgkb:PA164746560
> ;
dv:x-uniprot
<
http://bio2rdf.org/uniprot:P01225
> ;
dct:description
"Thyrotropin alfa is a recombinant form of thyroid stimulating hormone used in performing certain tests in patients who have or have had thyroid cancer. It is also used along with a radioactive agent to destroy remaining thyroid tissue in certain patients who have had their thyroid gland removed because of thyroid cancer. It is a heterodimeric glycoprotein comprised of two non-covalently linked subunits, an alpha subunit of 92 amino acid residues containing two N-linked glycosylation sites and a beta subunit of 112 residues containing one N-linked glycosylation site. The alpha subunit is nearly identical to that of human chorionic gonadotropin (hCG), luteinizing hormone (LH), and follicle-stimulating hormone (FSH). The alpha subunit is thought to be the effector region responsible for stimulation of adenylate cyclase (involved the generation of cAMP). The beta subunit (TSHB) is unique to TSH, and therefore determines its receptor specificity. The amino acid sequence of thyrotropin alfa is identical to that of human pituitary thyroid stimulating hormone."@en ;
dct:identifier
"drugbank:DB00024" ;
dct:title
"Thyrotropin Alfa"@en ;
a
dv:Drug
;
rdfs:label
"Thyrotropin Alfa [drugbank:DB00024]"@en ;
rdfs:seeAlso
<
http://www.drugbank.ca/drugs/DB00024
> , <
http://www.drugs.com/cdi/thyrotropin-alfa.html
> , <
http://www.rxlist.com/cgi/generic2/thyrotropin.htm
> .
}
sub:provenance
{
sub:assertion
prov:wasDerivedFrom
<
http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz
> .
dr:bio2rdf.dataset.drugbank.R3
dcat:distribution
<
http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz
> .
<
http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz
>
dct:created
"2015-01-09T17:00:50-05:00"^^
xsd:dateTime
;
prov:wasDerivedFrom
<
http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip#retrieved-on:2014-11-12T07:57:03-05:00
> .
<
http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip#retrieved-on:2014-11-12T07:57:03-05:00
>
pav:retrievedOn
"2014-11-12T07:57:03-05:00"^^
xsd:dateTime
;
prov:wasDerivedFrom
<
http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip
> .
<
http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip
>
prov:wasAttributedTo
<
http://drugbank.ca
> .
}
sub:publicationInfo
{
sub:signature.MC0CFQCOGI2LKX00
npx:hasPublicKey
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npx:hasSignature
"MC0CFQCOGI2LKX00bsjemJZ/zxbeWN5inAIUJAMKSBKuVkcoKBXpH8ZUjOYCgzM=" ;
npx:signedBy
instance:
.
this:
dct:created
"2018-03-30T11:10:52.275+02:00"^^
xsd:dateTime
;
dct:license
<
https://creativecommons.org/licenses/by-nc/4.0/
> ;
npx:hasSignatureElement
sub:signature.MC0CFQCOGI2LKX00
;
prov:wasGeneratedBy
process:
.
instance:
prov:specializationOf
codebase:
;
prov:wasAttributedTo
orcid:0000-0002-1267-0234
.
process:
dct:identifier
"7720f136-841b-4851-a6e4-ad20a409a475" ;
prov:used
version:
;
prov:wasAssociatedWith
instance:
;
prov:wasStartedBy
orcid:0000-0002-1267-0234
.
version:
dct:isVersionOf
codebase:
;
pav:version
"eda7951a5f6c622c5d2132f50c3093138484a349" ;
prov:wasAttributedTo
orcid:0000-0002-1267-0234
.
}