sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_6 ;
    pav:version "1.4" .
  sub:_5 prov:value "In lean mice and db/db mice, injection of insulin produced rapid tyrosine phosphorylation of insulin receptor substrate 1 (IRS-1), recruitment of p85, the regulatory subunit of phosphatidylinositol 3-kinase and phosphorylation of the downstream signaling molecule Akt. CNTF (0.1 mg/kg per day or 0.3 mg/kg per day) treatment increased hepatic insulin sensitivity as evidenced by the activation of AKT, a downstream molecule of PI3K. However, food restriction alone failed to improve hepatic insulin sensitivity." ;
    prov:wasQuotedFrom pubmed:14610276 .
  sub:_6 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:14610276 ;
    prov:wasDerivedFrom beldoc: , sub:_5 .
}