sub:provenance { beldoc:dce:description "Approximately 61,000 statements." ; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ; dce:title "BEL Framework Large Corpus Document" ; pav:authoredBysub:_4 ; pav:version "20131211" . sub:_3prov:value "In a recent study by Meyer-Siegler et al. [52] , MIF influenced cell viability and invasiveness. In prostate cancer cells, androgen-independent prostate cancer cells required MIF-activated signal transduction pathways for both growth and invasion, which was in contrast to androgen- dependent cells. They demonstrated that the MIF cell surface receptor CD74 was only detected in androgen- independent tumor cells. Treatments directed against either CD74 or MIF resulted in decreased cell proliferation, MIF secretion and invasion." ; prov:wasQuotedFrompubmed:18791328 . sub:_4rdfs:label "Selventa" . sub:assertionprov:hadPrimarySourcepubmed:18791328 ; prov:wasDerivedFrombeldoc: , sub:_3 . }