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All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RA0PtlsibKn7lzxN8ZpLVi6hc1i4bR52j4XOpqKIGQU44#_6 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RA0PtlsibKn7lzxN8ZpLVi6hc1i4bR52j4XOpqKIGQU44#_5 http://www.w3.org/ns/prov#value Myogenin expression, and not MyoD, was found to up-regulate MEF2C expression. MEF2A, -B, and -D expression levels were not up-regulated by overexpression of either MyoD or myogenin. To examine whether MEF2C can differentially regulate MyoD or myogenin expression, P19 cell lines overexpressing MEF2C were analyzed. MEF2C induced myogenesis in P19 cells and up-regulated the expression of myogenin with 25-fold greater efficiency than that of MyoD. Therefore, myogenin and MEF2C participate in a regulatory loop in differentiating stem cells. http://www.tkuhn.ch/bel2nanopub/RA0PtlsibKn7lzxN8ZpLVi6hc1i4bR52j4XOpqKIGQU44#_5 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/10617583 http://www.tkuhn.ch/bel2nanopub/RA0PtlsibKn7lzxN8ZpLVi6hc1i4bR52j4XOpqKIGQU44#_6 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RA0PtlsibKn7lzxN8ZpLVi6hc1i4bR52j4XOpqKIGQU44#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/10617583 http://www.tkuhn.ch/bel2nanopub/RA0PtlsibKn7lzxN8ZpLVi6hc1i4bR52j4XOpqKIGQU44#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RA0PtlsibKn7lzxN8ZpLVi6hc1i4bR52j4XOpqKIGQU44#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RA0PtlsibKn7lzxN8ZpLVi6hc1i4bR52j4XOpqKIGQU44#_5 http://www.tkuhn.ch/bel2nanopub/RA0PtlsibKn7lzxN8ZpLVi6hc1i4bR52j4XOpqKIGQU44#pubinfo http://www.tkuhn.ch/bel2nanopub/RA0PtlsibKn7lzxN8ZpLVi6hc1i4bR52j4XOpqKIGQU44 http://purl.org/dc/terms/created 2014-07-03T14:31:33.463+02:00 http://www.tkuhn.ch/bel2nanopub/RA0PtlsibKn7lzxN8ZpLVi6hc1i4bR52j4XOpqKIGQU44 http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RA0PtlsibKn7lzxN8ZpLVi6hc1i4bR52j4XOpqKIGQU44 http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234