. . . . . . . . . . . . . . "p(MGI:Pias1) =| tscript(complex(NCM:\"Nfkb Complex\"))" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "1.4" . "PIAS1 inhibits TNF-{alpha}-induced NF-{kappa}B-dependent gene activation. (A) Luciferase (Luc.) reporter assays. Human 293T cells (left) or lung cancer A549 cells (right) were transiently transfected with luciferase reporter construct 2xNF-{kappa}B together with increasing amounts of Flag-PIAS1. Twenty-four hours posttransfection, cells were either untreated (gray bar) or treated with TNF-{alpha} for 6 h (black bar), and cell lysates were subjected to luciferase assays. Shown is the average of results from three independent experiments. Pias1 decreases NFkappaB activity in a dose dependent manner. " . . "Selventa" . . . . "2014-07-03T14:30:30.963+02:00"^^ . . .