sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_5 ;
    pav:version "1.4" .
  sub:_4 prov:value "PIAS1 inhibits TNF-{alpha}-induced NF-{kappa}B-dependent gene activation. (A) Luciferase (Luc.) reporter assays. Human 293T cells (left) or lung cancer A549 cells (right) were transiently transfected with luciferase reporter construct 2xNF-{kappa}B together with increasing amounts of Flag-PIAS1. Twenty-four hours posttransfection, cells were either untreated (gray bar) or treated with TNF-{alpha} for 6 h (black bar), and cell lysates were subjected to luciferase assays. Shown is the average of results from three independent experiments. Pias1 decreases NFkappaB activity in a dose dependent manner. " ;
    prov:wasQuotedFrom pubmed:15657437 .
  sub:_5 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:15657437 ;
    prov:wasDerivedFrom beldoc: , sub:_4 .
}