. . . . . . . . . . . . . . . . "complex(p(HGNC:PAWR),p(HGNC:DAXX)) -> bp(MESHPP:Apoptosis)" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "1.4" . "These findings suggest that Par-4, Daxx, and ZIPK may form a ternary complex, though further work is required to verify this hypothesis. ZIPK, Daxx, and Par-4 collaborate in caspase activation and apoptosis induction. Cells transfected individually with plasmids encoding ZIPK, Par-4, or Daxx did not exhibit an increase in apoptosis at the concentrations of plasmid DNA used here (Fig. 6A). In contrast, the percentage of apoptotic cells was increased two- to threefold in cultures of cells coexpressing ZIPK with either Par-4 or Daxx (Fig. 6A). Similarly, coexpressing Daxx with Par-4 elevated the percentage of apoptotic cells by two to threefold compared to the percentage due to expression of either Daxx or Par-4 alone (Fig. 6A). The most striking increase in apoptosis, however, was achieved by expressing all three proteins together. When expressed together, ZIPK, Daxx, and Par-4 induced an approximately sixfold increase in apoptosis." . . "Selventa" . . . . "2014-07-03T14:30:15.523+02:00"^^ . . .