. . . . . . . . . . . . "[Consequently, we assessed the methylation status of CDKN2A/p16, MGMT, MLH1 and p14(ARF) in adenomas arising in the Lynch syndrome, a familial colon cancer syndrome caused by MLH1 and MSH2 mutations, to determine if DNA methylation is a 'second hit' mechanism in CRC and to characterize the role of DNA methylation in the polyp phase of the Lynch syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2015-02-27"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2015-08-25T14:43:19+02:00"^^ . . . . . . . . . . . "v3.0.0.0" . "v3.0.0" .