http://bio2rdf.org/drugbank:DB04983_nanopub.RA-a-amY4NXylmS8OXHSdaVmPt0Goteg3Oe2LrfmJ0NWE#head http://bio2rdf.org/drugbank:DB04983_nanopub.RA-a-amY4NXylmS8OXHSdaVmPt0Goteg3Oe2LrfmJ0NWE http://www.nanopub.org/nschema#hasAssertion http://bio2rdf.org/drugbank:DB04983_nanopub.RA-a-amY4NXylmS8OXHSdaVmPt0Goteg3Oe2LrfmJ0NWE#assertion http://bio2rdf.org/drugbank:DB04983_nanopub.RA-a-amY4NXylmS8OXHSdaVmPt0Goteg3Oe2LrfmJ0NWE http://www.nanopub.org/nschema#hasProvenance http://bio2rdf.org/drugbank:DB04983_nanopub.RA-a-amY4NXylmS8OXHSdaVmPt0Goteg3Oe2LrfmJ0NWE#provenance http://bio2rdf.org/drugbank:DB04983_nanopub.RA-a-amY4NXylmS8OXHSdaVmPt0Goteg3Oe2LrfmJ0NWE http://www.nanopub.org/nschema#hasPublicationInfo http://bio2rdf.org/drugbank:DB04983_nanopub.RA-a-amY4NXylmS8OXHSdaVmPt0Goteg3Oe2LrfmJ0NWE#publicationInfo http://bio2rdf.org/drugbank:DB04983_nanopub.RA-a-amY4NXylmS8OXHSdaVmPt0Goteg3Oe2LrfmJ0NWE http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://bio2rdf.org/drugbank:DB04983_nanopub.RA-a-amY4NXylmS8OXHSdaVmPt0Goteg3Oe2LrfmJ0NWE#assertion http://bio2rdf.org/drugbank:DB04983 http://bio2rdf.org/bio2rdf_vocabulary:identifier DB04983 http://bio2rdf.org/drugbank:DB04983 http://bio2rdf.org/bio2rdf_vocabulary:namespace drugbank http://bio2rdf.org/drugbank:DB04983 http://bio2rdf.org/bio2rdf_vocabulary:uri http://bio2rdf.org/drugbank:DB04983 http://bio2rdf.org/drugbank:DB04983 http://bio2rdf.org/bio2rdf_vocabulary:x-identifiers.org http://identifiers.org/drugbank/DB04983 http://bio2rdf.org/drugbank:DB04983 http://bio2rdf.org/drugbank_vocabulary:drugbank-id DB04983 http://bio2rdf.org/drugbank:DB04983 http://bio2rdf.org/drugbank_vocabulary:x-cas http://bio2rdf.org/cas:318250-11-2 http://bio2rdf.org/drugbank:DB04983 http://bio2rdf.org/drugbank_vocabulary:x-kegg http://bio2rdf.org/kegg:D03685 http://bio2rdf.org/drugbank:DB04983 http://purl.org/dc/terms/description Denufosol (INN) is an inhaled drug for the treatment of cystic fibrosis, being developed by Inspire Pharmaceuticals and sponsored by the Cystic Fibrosis Foundation. It was tested in two Phase III clinical trials, TIGER-1 and TIGER-2. Initially, in the first Phase III trial, TIGER-1, the compound showed significant results as compared with placebo. In the second Phase III trial, TIGER-2, the compound did not meet the primary endpoint, a significant change in baseline FEV1 (forced expiratory volume in one second) at the week 48 endpoint as compared to placebo. As of 2011, no additional clinical studies are being conducted with the compound. The drug was also investigated for the treatment of retinal detachment and other retinal diseases, but trials were terminated in 2006. [Wikipedia] http://bio2rdf.org/drugbank:DB04983 http://purl.org/dc/terms/identifier drugbank:DB04983 http://bio2rdf.org/drugbank:DB04983 http://purl.org/dc/terms/title Denufosol http://bio2rdf.org/drugbank:DB04983 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://bio2rdf.org/drugbank_vocabulary:Drug http://bio2rdf.org/drugbank:DB04983 http://www.w3.org/2000/01/rdf-schema#label Denufosol [drugbank:DB04983] http://bio2rdf.org/drugbank:DB04983 http://www.w3.org/2000/01/rdf-schema#seeAlso http://www.drugbank.ca/drugs/DB04983 http://bio2rdf.org/drugbank:DB04983_nanopub.RA-a-amY4NXylmS8OXHSdaVmPt0Goteg3Oe2LrfmJ0NWE#provenance http://bio2rdf.org/drugbank:DB04983_nanopub.RA-a-amY4NXylmS8OXHSdaVmPt0Goteg3Oe2LrfmJ0NWE#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz http://bio2rdf.org/drugbank_resource:bio2rdf.dataset.drugbank.R3 http://www.w3.org/ns/dcat#distribution http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz http://purl.org/dc/terms/created 2015-01-09T17:00:50-05:00 http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz http://www.w3.org/ns/prov#wasDerivedFrom http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip#retrieved-on:2014-11-12T07:57:03-05:00 http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip#retrieved-on:2014-11-12T07:57:03-05:00 http://purl.org/pav/retrievedOn 2014-11-12T07:57:03-05:00 http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip#retrieved-on:2014-11-12T07:57:03-05:00 http://www.w3.org/ns/prov#wasDerivedFrom http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip http://www.w3.org/ns/prov#wasAttributedTo http://drugbank.ca http://bio2rdf.org/drugbank:DB04983_nanopub.RA-a-amY4NXylmS8OXHSdaVmPt0Goteg3Oe2LrfmJ0NWE#publicationInfo http://bio2rdf.org/drugbank:DB04983_nanopub.RA-a-amY4NXylmS8OXHSdaVmPt0Goteg3Oe2LrfmJ0NWE#signature.MC0CFFOS7iU0J815 http://purl.org/nanopub/x/hasPublicKey MIIBtzCCASwGByqGSM44BAEwggEfAoGBAP1/U4EddRIpUt9KnC7s5Of2EbdSPO9EAMMeP4C2USZpRV1AIlH7WT2NWPq/xfW6MPbLm1Vs14E7gB00b/JmYLdrmVClpJ+f6AR7ECLCT7up1/63xhv4O1fnxqimFQ8E+4P208UewwI1VBNaFpEy9nXzrith1yrv8iIDGZ3RSAHHAhUAl2BQjxUjC8yykrmCouuEC/BYHPUCgYEA9+GghdabPd7LvKtcNrhXuXmUr7v6OuqC+VdMCz0HgmdRWVeOutRZT+ZxBxCBgLRJFnEj6EwoFhO3zwkyjMim4TwWeotUfI0o4KOuHiuzpnWRbqN/C/ohNWLx+2J6ASQ7zKTxvqhRkImog9/hWuWfBpKLZl6Ae1UlZAFMO/7PSSoDgYQAAoGAETGrDm8R3KfndKRj7ttr3jVhhstI6/2Ey0ER9F5kdx7Hrd6eolq7yWzPzf2H754tdZxICzxYcdawBbL2ZUzFjWwXTNUQC3+e6evKPJyNELubnZcA+8TxIIwicBnw3Ku6mSeI8SUVr5SBV1VeJoSu/ahldv562IdBR8IagmzuT3Y= http://bio2rdf.org/drugbank:DB04983_nanopub.RA-a-amY4NXylmS8OXHSdaVmPt0Goteg3Oe2LrfmJ0NWE#signature.MC0CFFOS7iU0J815 http://purl.org/nanopub/x/hasSignature MC0CFFOS7iU0J815x+WjtFHOteJy9UAnAhUAgBgpw7p3OhKQDVLCHutjm2GN8MU= http://bio2rdf.org/drugbank:DB04983_nanopub.RA-a-amY4NXylmS8OXHSdaVmPt0Goteg3Oe2LrfmJ0NWE#signature.MC0CFFOS7iU0J815 http://purl.org/nanopub/x/signedBy https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB http://bio2rdf.org/drugbank:DB04983_nanopub.RA-a-amY4NXylmS8OXHSdaVmPt0Goteg3Oe2LrfmJ0NWE http://purl.org/dc/terms/created 2018-03-30T11:10:53.268+02:00 http://bio2rdf.org/drugbank:DB04983_nanopub.RA-a-amY4NXylmS8OXHSdaVmPt0Goteg3Oe2LrfmJ0NWE http://purl.org/dc/terms/license https://creativecommons.org/licenses/by-nc/4.0/ http://bio2rdf.org/drugbank:DB04983_nanopub.RA-a-amY4NXylmS8OXHSdaVmPt0Goteg3Oe2LrfmJ0NWE http://purl.org/nanopub/x/hasSignatureElement http://bio2rdf.org/drugbank:DB04983_nanopub.RA-a-amY4NXylmS8OXHSdaVmPt0Goteg3Oe2LrfmJ0NWE#signature.MC0CFFOS7iU0J815 http://bio2rdf.org/drugbank:DB04983_nanopub.RA-a-amY4NXylmS8OXHSdaVmPt0Goteg3Oe2LrfmJ0NWE http://www.w3.org/ns/prov#wasGeneratedBy https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB.7720f136-841b-4851-a6e4-ad20a409a475 https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB http://www.w3.org/ns/prov#specializationOf https://github.com/tkuhn/bio2rdf2nanopub https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB http://www.w3.org/ns/prov#wasAttributedTo http://orcid.org/0000-0002-1267-0234 https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB.7720f136-841b-4851-a6e4-ad20a409a475 http://purl.org/dc/terms/identifier 7720f136-841b-4851-a6e4-ad20a409a475 https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB.7720f136-841b-4851-a6e4-ad20a409a475 http://www.w3.org/ns/prov#used https://github.com/tkuhn/bio2rdf2nanopub/tree/eda7951a5f6c622c5d2132f50c3093138484a349 https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB.7720f136-841b-4851-a6e4-ad20a409a475 http://www.w3.org/ns/prov#wasAssociatedWith https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB.7720f136-841b-4851-a6e4-ad20a409a475 http://www.w3.org/ns/prov#wasStartedBy http://orcid.org/0000-0002-1267-0234 https://github.com/tkuhn/bio2rdf2nanopub/tree/eda7951a5f6c622c5d2132f50c3093138484a349 http://purl.org/dc/terms/isVersionOf https://github.com/tkuhn/bio2rdf2nanopub https://github.com/tkuhn/bio2rdf2nanopub/tree/eda7951a5f6c622c5d2132f50c3093138484a349 http://purl.org/pav/version eda7951a5f6c622c5d2132f50c3093138484a349 https://github.com/tkuhn/bio2rdf2nanopub/tree/eda7951a5f6c622c5d2132f50c3093138484a349 http://www.w3.org/ns/prov#wasAttributedTo http://orcid.org/0000-0002-1267-0234