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[We describe the `LEOPARD syndrome (LS) phenotype` associated with the Gln510Glu mutation of the PTPN11 gene in two patients presenting with rapidly progressive severe biventricular obstructive hypertrophic cardiomyopathy and structural abnormalities of the mitral valve, facial anomalies, café-au-lait spots and multiple lentigines.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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