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complex(a(CHEBI:"arachidonic acid"),p(MGI:Pparg)) -> tscript(p(MGI:Pparg))
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Approximately 61,000 statements.
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Copyright (c) 2011-2012, Selventa. All rights reserved.
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BEL Framework Large Corpus Document
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In Mo exposed to AA, LA, and PA, an increase in Mo LPL synthetic rate was observed. ...enhanced binding of nuclear proteins extracted from all FA-treated Mo to the peroxisome proliferator-response element (PPRE) consensus sequence of the LPL promoter....Of the unsaturated FA's tested in the present study, LA and OA show high affinity for Ppara, whereas AA and EPA interact more efficiently with Pparg...Although our results demonstrate that PPAR- binding to the PPRE sequence occurs in AA-treated Mo, this does not provide evidence for a role of this transcription factor in the EPA-induced DNA binding activity to the PPRE sequence.
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Selventa
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2014-07-03T14:31:40.169+02:00
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