sub:provenance { beldoc:dce:description "Approximately 61,000 statements." ; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ; dce:title "BEL Framework Large Corpus Document" ; pav:authoredBysub:_5 ; pav:version "20131211" . sub:_4prov:value "In 2006, Baugh et al. [57] further revealed a possible role of MIF under hypoxic conditions. They describe HIF-1 as a potent inducer of MIF expression in hypoxia. Interestingly, these data were complemented by the works of Welford et al. [58] . They described the importance of HIF-1 in preventing cell senescence in a fibroblast model. Using HIF-1 knockout mice, they were able to show that under aerobic conditions lack of HIF-1 resulted in accelerated cellular aging and decreased cell proliferation under hypoxic conditions." ; prov:wasQuotedFrompubmed:18791328 . sub:_5rdfs:label "Selventa" . sub:assertionprov:hadPrimarySourcepubmed:18791328 ; prov:wasDerivedFrombeldoc: , sub:_4 . }