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[In this study, we determined that the level of apoptosis signal-regulating kinase 1 (ASK1) was lower in a metastatic breast cancer cell line, compared to that of non-metastatic cancer cell lines and the knockdown of ASK1 not only induces ?-catenin activation via the inhibition of GSK-3? and collapsing the subsequent protein complex by regulating Axin dynamics, but also stimulates cell migration.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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