http://rdf.disgenet.org/resource/nanopub/NP55084.RAvjPGliAaH_hyngzGvMKTEKzu2qpVd4Mg5ic6vIrqoVY#head
http://rdf.disgenet.org/resource/nanopub/NP55084.RAvjPGliAaH_hyngzGvMKTEKzu2qpVd4Mg5ic6vIrqoVY
http://www.nanopub.org/nschema#hasAssertion
http://rdf.disgenet.org/resource/nanopub/NP55084.RAvjPGliAaH_hyngzGvMKTEKzu2qpVd4Mg5ic6vIrqoVY#assertion
http://rdf.disgenet.org/resource/nanopub/NP55084.RAvjPGliAaH_hyngzGvMKTEKzu2qpVd4Mg5ic6vIrqoVY
http://www.nanopub.org/nschema#hasProvenance
http://rdf.disgenet.org/resource/nanopub/NP55084.RAvjPGliAaH_hyngzGvMKTEKzu2qpVd4Mg5ic6vIrqoVY#provenance
http://rdf.disgenet.org/resource/nanopub/NP55084.RAvjPGliAaH_hyngzGvMKTEKzu2qpVd4Mg5ic6vIrqoVY
http://www.nanopub.org/nschema#hasPublicationInfo
http://rdf.disgenet.org/resource/nanopub/NP55084.RAvjPGliAaH_hyngzGvMKTEKzu2qpVd4Mg5ic6vIrqoVY#publicationInfo
http://rdf.disgenet.org/resource/nanopub/NP55084.RAvjPGliAaH_hyngzGvMKTEKzu2qpVd4Mg5ic6vIrqoVY
http://www.w3.org/1999/02/22-rdf-syntax-ns#type
http://www.nanopub.org/nschema#Nanopublication
http://rdf.disgenet.org/resource/nanopub/NP55084.RAvjPGliAaH_hyngzGvMKTEKzu2qpVd4Mg5ic6vIrqoVY#assertion
http://rdf.disgenet.org/resource/gda/DGN4513b93ec43eca1cf17b55c1385ec30c
http://semanticscience.org/resource/SIO_000628
http://identifiers.org/ncbigene/338
http://rdf.disgenet.org/resource/gda/DGN4513b93ec43eca1cf17b55c1385ec30c
http://semanticscience.org/resource/SIO_000628
http://linkedlifedata.com/resource/umls/id/C0007820
http://rdf.disgenet.org/resource/gda/DGN4513b93ec43eca1cf17b55c1385ec30c
http://www.w3.org/1999/02/22-rdf-syntax-ns#type
http://semanticscience.org/resource/SIO_001122
http://rdf.disgenet.org/resource/nanopub/NP55084.RAvjPGliAaH_hyngzGvMKTEKzu2qpVd4Mg5ic6vIrqoVY#provenance
http://rdf.disgenet.org/resource/nanopub/NP55084.RAvjPGliAaH_hyngzGvMKTEKzu2qpVd4Mg5ic6vIrqoVY#assertion
http://purl.org/dc/terms/description
[The studies can be summarized as follows: (1) apolipoprotein B predicts ischemic cardiovascular events in both genders, and is better than LDL cholesterol in this respect; (2) linkage disequilibrium structure in APOB is more complex than expected from HapMap data, because a minimal set of tag single nucleotide polymorphisms capturing the entire variation in APOB cannot be identified, and thus most polymorphisms must be evaluated separately in association studies; (3) APOB mutations and polymorphisms are associated with a range of apolipoprotein B and LDL cholesterol levels, although the magnitude of effect sizes of common polymorphisms are modest; (4) both mutations and polymorphisms are associated with LDL metabolism in vivo; (5) association of APOB mutations and polymorphisms with lipid and disease phenotype cannot be predicted in silico using evolutionary conservation or existing prediction programs; and finally, (6) except for the E4154K polymorphism that possibly predicts a reduction in risk of ischemic cerebrovascular disease and ischemic stroke, common APOB polymorphisms with modest effect sizes on lipid levels do not predict risk of ischemic heart disease, myocardial infarction, ischemic cerebrovascular disease, or ischemic stroke in the general population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
http://rdf.disgenet.org/resource/nanopub/NP55084.RAvjPGliAaH_hyngzGvMKTEKzu2qpVd4Mg5ic6vIrqoVY#assertion
http://purl.org/ontology/wi/core#evidence
http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature
http://rdf.disgenet.org/resource/nanopub/NP55084.RAvjPGliAaH_hyngzGvMKTEKzu2qpVd4Mg5ic6vIrqoVY#assertion
http://semanticscience.org/resource/SIO_000772
http://identifiers.org/pubmed/19200547
http://rdf.disgenet.org/resource/nanopub/NP55084.RAvjPGliAaH_hyngzGvMKTEKzu2qpVd4Mg5ic6vIrqoVY#assertion
http://www.w3.org/ns/prov#wasDerivedFrom
http://rdf.disgenet.org/v5.0.0/void/BEFREE
http://rdf.disgenet.org/resource/nanopub/NP55084.RAvjPGliAaH_hyngzGvMKTEKzu2qpVd4Mg5ic6vIrqoVY#assertion
http://www.w3.org/ns/prov#wasGeneratedBy
http://purl.obolibrary.org/obo/ECO_0000203
http://rdf.disgenet.org/v5.0.0/void/BEFREE
http://purl.org/pav/importedOn
2017-02-19
http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature
http://www.w3.org/1999/02/22-rdf-syntax-ns#type
http://purl.obolibrary.org/obo/ECO_0000212
http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature
http://www.w3.org/2000/01/rdf-schema#comment
Gene-disease associations inferred from text-mining the literature.
http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature
http://www.w3.org/2000/01/rdf-schema#label
DisGeNET evidence - LITERATURE
http://rdf.disgenet.org/resource/nanopub/NP55084.RAvjPGliAaH_hyngzGvMKTEKzu2qpVd4Mg5ic6vIrqoVY#publicationInfo
http://rdf.disgenet.org/resource/nanopub/NP55084.RAvjPGliAaH_hyngzGvMKTEKzu2qpVd4Mg5ic6vIrqoVY
http://purl.org/dc/terms/created
2017-10-17T13:10:32+02:00
http://rdf.disgenet.org/resource/nanopub/NP55084.RAvjPGliAaH_hyngzGvMKTEKzu2qpVd4Mg5ic6vIrqoVY
http://purl.org/dc/terms/rights
http://opendatacommons.org/licenses/odbl/1.0/
http://rdf.disgenet.org/resource/nanopub/NP55084.RAvjPGliAaH_hyngzGvMKTEKzu2qpVd4Mg5ic6vIrqoVY
http://purl.org/dc/terms/rightsHolder
http://rdf.disgenet.org/v5.0.0/void/IBIGroup
http://rdf.disgenet.org/resource/nanopub/NP55084.RAvjPGliAaH_hyngzGvMKTEKzu2qpVd4Mg5ic6vIrqoVY
http://purl.org/dc/terms/subject
http://semanticscience.org/resource/SIO_000983
http://rdf.disgenet.org/resource/nanopub/NP55084.RAvjPGliAaH_hyngzGvMKTEKzu2qpVd4Mg5ic6vIrqoVY
http://purl.org/net/provenance/ns#usedData
http://rdf.disgenet.org/v5.0.0/void/disgenetv3.0rdf
http://rdf.disgenet.org/resource/nanopub/NP55084.RAvjPGliAaH_hyngzGvMKTEKzu2qpVd4Mg5ic6vIrqoVY
http://purl.org/pav/authoredBy
http://orcid.org/0000-0001-5999-6269
http://rdf.disgenet.org/resource/nanopub/NP55084.RAvjPGliAaH_hyngzGvMKTEKzu2qpVd4Mg5ic6vIrqoVY
http://purl.org/pav/authoredBy
http://orcid.org/0000-0002-7534-7661
http://rdf.disgenet.org/resource/nanopub/NP55084.RAvjPGliAaH_hyngzGvMKTEKzu2qpVd4Mg5ic6vIrqoVY
http://purl.org/pav/authoredBy
http://orcid.org/0000-0002-9383-528X
http://rdf.disgenet.org/resource/nanopub/NP55084.RAvjPGliAaH_hyngzGvMKTEKzu2qpVd4Mg5ic6vIrqoVY
http://purl.org/pav/authoredBy
http://orcid.org/0000-0003-0169-8159
http://rdf.disgenet.org/resource/nanopub/NP55084.RAvjPGliAaH_hyngzGvMKTEKzu2qpVd4Mg5ic6vIrqoVY
http://purl.org/pav/authoredBy
http://orcid.org/0000-0003-1244-7654
http://rdf.disgenet.org/resource/nanopub/NP55084.RAvjPGliAaH_hyngzGvMKTEKzu2qpVd4Mg5ic6vIrqoVY
http://purl.org/pav/createdBy
http://orcid.org/0000-0003-0169-8159
http://rdf.disgenet.org/resource/nanopub/NP55084.RAvjPGliAaH_hyngzGvMKTEKzu2qpVd4Mg5ic6vIrqoVY
http://purl.org/pav/version
v5.0.0.0
http://rdf.disgenet.org/v5.0.0/void/disgenetv3.0rdf
http://purl.org/pav/version
v5.0.0