@prefix biolink: <https://w3id.org/biolink/vocab/> .
@prefix ns1: <https://w3id.org/np/o/ntemplate/> .
@prefix this: <http://purl.org/np/RAu0zXQmdIOBMsbzHUdw8m67u3NCf_7rN9XGe3NL7QS38> .
@prefix sub: <http://purl.org/np/RAu0zXQmdIOBMsbzHUdw8m67u3NCf_7rN9XGe3NL7QS38#> .
@prefix schema: <https://schema.org/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix orcid: <https://orcid.org/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .
sub:Head {
  this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubinfo ;
    a np:Nanopublication .
}
sub:assertion {
  <http://purl.obolibrary.org/obo/DOID_2841> biolink:category biolink:Disease .
  sub:association rdf:object <http://purl.obolibrary.org/obo/DOID_2841> ;
    rdf:predicate biolink:treats ;
    rdf:subject <https://identifiers.org/drugbank:DB00981> ;
    a rdf:Statement ;
    rdfs:label "\"Physostigmine Salicylate Injection should not be used in the presence of asthma, gangrene, diabetes, cardiovascular disease, mechanical obstruction of the intestine or urogenital tract or any vagotonic state, and in patients receiving choline esters and depolarizing neuromuscular blocking agents (decamethonium, succinylcholine).   For post-anesthesia, the concomitant use of atropine with physostigmine salicylate is not recommended, since the atropine antagonizes the action of physostigmine.\"" ;
    biolink:provided_by <https://w3id.org/um/NeuroDKG> ;
    biolink:relation schema:MedicalContraindication .
  <https://identifiers.org/drugbank:DB00981> biolink:category biolink:Drug .
}
sub:provenance {
  sub:assertion prov:wasAttributedTo orcid:0000-0002-1468-3557 .
}
sub:pubinfo {
  sub:sig npx:hasAlgorithm "RSA" ;
    npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCODwZkXojpEKwk7Ldj2oPPfCstvqrcpgCaTLo235K7ht9C7E1GCkLvUuL2b4VWXJTcZx/hxgDauR8hUeYq/lS6tfTL9yFZsnfl+PWYDyz7vv6N+wJVx2LL8bO6ntCjcOzvW2t2WUeF12Sb6b3I6uOYP0N8iQKts1WasY/yEYKAHQIDAQAB" ;
    npx:hasSignature "XgCzBu6OmAoYnW5UJti3l/KydcJU/LfQWrknjx9ywbjGmSXGrvoTEOY+XYeN0Mn+mg9r1qMqKIIwc8Ucj+D2zXFE9UbGY0Azu/AsjSP2glQEUtYM7Sf4Q2tahf9YQVlYefWakBMWvKmCgiEM8R7zGa6PfQ1iHWmzhCVXorj8Zd4=" ;
    npx:hasSignatureTarget this: .
  this: dct:created "2021-08-25T14:32:22.426+02:00"^^xsd:dateTime ;
    dct:creator orcid:0000-0002-1468-3557 ;
    ns1:wasCreatedFromProvenanceTemplate <http://purl.org/np/RANwQa4ICWS5SOjw7gp99nBpXBasapwtZF1fIM3H2gYTM> ;
    ns1:wasCreatedFromPubinfoTemplate <http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM> ;
    ns1:wasCreatedFromTemplate <http://purl.org/np/RAhNHZw6Urw_Mccs4qy6Ws3C9CRuaHpQx8AwuApbWkqnY> .
}