@prefix nkg: <https://w3id.org/um/neurodkg/> .
@prefix nt: <https://w3id.org/np/o/ntemplate/> .
@prefix orcid: <https://orcid.org/> .
@prefix bl: <https://w3id.org/biolink/vocab/> .
@prefix this: <http://purl.org/np/RAt67boJRGO1ZeTI3qjRCPwNRjM1dPU6tbYpfp7Rp0VMc> .
@prefix sub: <http://purl.org/np/RAt67boJRGO1ZeTI3qjRCPwNRjM1dPU6tbYpfp7Rp0VMc#> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubInfo;
    a np:Nanopublication .
}

sub:assertion {
  <http://purl.obolibrary.org/obo/MONDO_0007661> a bl:Disease .
  
  sub:association rdf:object <http://purl.obolibrary.org/obo/MONDO_0007661>;
    rdf:predicate bl:treats;
    rdf:subject <https://identifiers.org/DRUGBANK:DB01267>;
    a rdf:Statement;
    rdfs:label "Yamamuro et al. [13] have reported on 3 CAP cases with TS treated with paliperidone. In 2 cases, TS symptoms were remark- ably improved by switching from haloperidol to paliperidone ex- tended release, and in another case, paliperidone-extended release showed significant efficacy in treating TS symptoms as the first-line drug.";
    bl:has_population_context sub:context;
    bl:provided_by <https://w3id.org/um/NeuroDKG>;
    bl:publications <https://pubmed.ncbi.nlm.nih.gov/31096228>;
    bl:relation nkg:OffLabelIndication .
  
  sub:context a bl:Cohort;
    rdfs:label "Children and adolescents" .
  
  <https://identifiers.org/DRUGBANK:DB01267> a bl:Drug .
}

sub:provenance {
  sub:assertion prov:generatedAtTime "2021-08-24T16:13:45.354608"^^xsd:dateTime .
}

sub:pubInfo {
  sub:sig npx:hasAlgorithm "RSA";
    npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCamPJb4SzqpLXn//XJ5dlVfzz6QI+RPmiJTLXF/by2JR7sHMKRsCQDFsYMlq8zGHghOIkjRP9dpLZUtZzUcHt3MXiFKEPo8eGzUe9p+JXKFC8xxkJr94z2vq6IdMf71Iu1GH8SeDAKt/DgYO4zNaw8VuXvxnZRewKZSA+u8zWPVwIDAQAB";
    npx:hasSignature "Chzvzw8RIsiw0c9qUgKGiX/aBrwVx/PuWbALvwUI6ZAEXcS4YXh7wTsZ9tKz2be+8DvF2r+UTgRdfyKwNM+Vt26H5IVR6sVUYGg5T3Ned925zkjT14mk6MLsszM9HmBBtKYcSgieGrJuLlr5RCoLfCHMTZjsWt9IN2PDjssU/zY=";
    npx:hasSignatureTarget this: .
  
  this: prov:generatedAtTime "2021-08-24T16:13:45.354608"^^xsd:dateTime;
    prov:wasAttributedTo orcid:0000-0002-7641-6446;
    nt:wasCreatedFromTemplate <http://purl.org/np/RAhNHZw6Urw_Mccs4qy6Ws3C9CRuaHpQx8AwuApbWkqnY> .
}