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The same genotypes of these single nucleotide polymorphisms (SNPs) that are associated with reduced 25(OH)D3 serum levels were found to be associated with HCV-related HCC (P?=?0.07 [OR?=?1.13, 95% CI?=?0.99-1.28] for CYP2R1, P?=?0.007 [OR?=?1.56, 95% CI?=?1.12-2.15] for GC, P?=?0.003 [OR?=?1.42, 95% CI?=?1.13-1.78] for DHCR7; ORs for risk genotypes).]. 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