@prefix dcterms: <
http://purl.org/dc/terms/
> .
@prefix ns1: <
http://www.w3.org/ns/prov#
> .
@prefix this: <
http://purl.org/np/RAq6vhTfnr8C6dt3KhdzV7tusjSHtHX5ab0r9qXYL3y2Y
> .
@prefix sub: <
http://purl.org/np/RAq6vhTfnr8C6dt3KhdzV7tusjSHtHX5ab0r9qXYL3y2Y#
> .
@prefix schema: <
https://schema.org/
> .
@prefix np: <
http://www.nanopub.org/nschema#
> .
@prefix rdf: <
http://www.w3.org/1999/02/22-rdf-syntax-ns#
> .
@prefix nt: <
https://w3id.org/np/o/ntemplate/
> .
@prefix xsd: <
http://www.w3.org/2001/XMLSchema#
> .
@prefix rdfs: <
http://www.w3.org/2000/01/rdf-schema#
> .
@prefix orcid: <
https://orcid.org/
> .
@prefix bl: <
https://w3id.org/biolink/vocab/
> .
@prefix npx: <
http://purl.org/nanopub/x/
> .
sub:Head
{
this:
np:hasAssertion
sub:assertion
;
np:hasProvenance
sub:provenance
;
np:hasPublicationInfo
sub:pubinfo
;
a
np:Nanopublication
.
}
sub:assertion
{
<
http://purl.obolibrary.org/obo/DOID_1067
>
bl:category
bl:Disease
.
sub:association
rdf:object
<
http://purl.obolibrary.org/obo/DOID_1067
> ;
rdf:predicate
bl:treats
;
rdf:subject
<
https://identifiers.org/drugbank:DB00195
> ;
a
rdf:Statement
;
rdfs:label
"betaxolol hydrochloride ophthalmic solution has been shown to be effective in lowering intraocular pressure and is indicated in the treatment of ocular hypertension and chronic open angle glaucoma it may be used alone or in combination with other anti glaucoma drugs in clinical studies betaxolol hydrochloride ophthalmic solution was safely used to lower intraocular pressure in 47 patients with both glaucoma and reactive airway disease who were followed for a mean period of 15 months however caution should be used in treating patients with severe reactive airway disease or a history of asthma" ;
bl:association_type
bl:ChemicalToDiseaseOrPhenotypicFeatureAssociation
;
bl:provided_by
<
https://w3id.org/um/NeuroDKG
> ;
bl:relation
schema:TreatmentIndication
.
<
https://identifiers.org/drugbank:DB00195
>
bl:category
bl:Drug
.
}
sub:provenance
{
sub:assertion
ns1:wasAttributedTo
orcid:0000-0002-1468-3557
.
}
sub:pubinfo
{
sub:sig
npx:hasAlgorithm
"RSA" ;
npx:hasPublicKey
"MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCODwZkXojpEKwk7Ldj2oPPfCstvqrcpgCaTLo235K7ht9C7E1GCkLvUuL2b4VWXJTcZx/hxgDauR8hUeYq/lS6tfTL9yFZsnfl+PWYDyz7vv6N+wJVx2LL8bO6ntCjcOzvW2t2WUeF12Sb6b3I6uOYP0N8iQKts1WasY/yEYKAHQIDAQAB" ;
npx:hasSignature
"iXmv2+dzaXzmWVw5XO6ggojzWnIyBRRsT2lxDi4kWhkWD6GmlI/S6M96dNPNAoZ6GocK4xz/dMegoyBxwNZmNpC6DS9aof5UHMHbs35tVf68dvvtlV1K4n2h02dA/FrffSckckVncXRGxHlz3/UOunWcP+T4mRx9nFPyQ3M05eE=" ;
npx:hasSignatureTarget
this:
.
this:
dcterms:created
"2021-06-27T21:42:56.298+02:00"^^
xsd:dateTime
;
dcterms:creator
orcid:0000-0002-1468-3557
;
nt:wasCreatedFromProvenanceTemplate
<
http://purl.org/np/RANwQa4ICWS5SOjw7gp99nBpXBasapwtZF1fIM3H2gYTM
> ;
nt:wasCreatedFromPubinfoTemplate
<
http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM
> ;
nt:wasCreatedFromTemplate
<
http://purl.org/np/RAManV5GZI01JKzW_IPcfOXoiFTcZMmsV7qTCLkdzr4Gs
> .
}