http://rdf.disgenet.org/resource/nanopub/NP1150743.RAmhfljqI2uB50VOgwPHD1jgWZajvpN7oLhLAIrWdiByw#head http://rdf.disgenet.org/resource/nanopub/NP1150743.RAmhfljqI2uB50VOgwPHD1jgWZajvpN7oLhLAIrWdiByw http://www.nanopub.org/nschema#hasAssertion http://rdf.disgenet.org/resource/nanopub/NP1150743.RAmhfljqI2uB50VOgwPHD1jgWZajvpN7oLhLAIrWdiByw#assertion http://rdf.disgenet.org/resource/nanopub/NP1150743.RAmhfljqI2uB50VOgwPHD1jgWZajvpN7oLhLAIrWdiByw http://www.nanopub.org/nschema#hasProvenance http://rdf.disgenet.org/resource/nanopub/NP1150743.RAmhfljqI2uB50VOgwPHD1jgWZajvpN7oLhLAIrWdiByw#provenance http://rdf.disgenet.org/resource/nanopub/NP1150743.RAmhfljqI2uB50VOgwPHD1jgWZajvpN7oLhLAIrWdiByw http://www.nanopub.org/nschema#hasPublicationInfo http://rdf.disgenet.org/resource/nanopub/NP1150743.RAmhfljqI2uB50VOgwPHD1jgWZajvpN7oLhLAIrWdiByw#publicationInfo http://rdf.disgenet.org/resource/nanopub/NP1150743.RAmhfljqI2uB50VOgwPHD1jgWZajvpN7oLhLAIrWdiByw http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://rdf.disgenet.org/resource/nanopub/NP1150743.RAmhfljqI2uB50VOgwPHD1jgWZajvpN7oLhLAIrWdiByw#assertion http://rdf.disgenet.org/resource/gda/DGN054a4b0542b6c7efa7240ef12a3b94f6 http://semanticscience.org/resource/SIO_000628 http://identifiers.org/ncbigene/8626 http://rdf.disgenet.org/resource/gda/DGN054a4b0542b6c7efa7240ef12a3b94f6 http://semanticscience.org/resource/SIO_000628 http://linkedlifedata.com/resource/umls/id/C0028754 http://rdf.disgenet.org/resource/gda/DGN054a4b0542b6c7efa7240ef12a3b94f6 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://semanticscience.org/resource/SIO_001122 http://rdf.disgenet.org/resource/nanopub/NP1150743.RAmhfljqI2uB50VOgwPHD1jgWZajvpN7oLhLAIrWdiByw#provenance http://rdf.disgenet.org/resource/nanopub/NP1150743.RAmhfljqI2uB50VOgwPHD1jgWZajvpN7oLhLAIrWdiByw#assertion http://purl.org/dc/terms/description [As tested with 12 obesity-causing human MC4R variants including S58C, E61K, N62S, I69T, P78L, C84R, G98R, T162I, R165W, W174C, C271Y, and P299H, Ipsen 17 was found to be the most universal pharmacological chaperone of MC4R reported so far because it can completely rescue nearly all mutant receptors (except P299H) with the highest potency (an EC50 value of approximately 10(-8)?M) and efficiency when compared with results for other tested pharmacological chaperones of MC4R including ML00253764, PBA, MTHP, PPPone, MPCI, DCPMP, and NBP described in the literature.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine. http://rdf.disgenet.org/resource/nanopub/NP1150743.RAmhfljqI2uB50VOgwPHD1jgWZajvpN7oLhLAIrWdiByw#assertion http://purl.org/ontology/wi/core#evidence http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature http://rdf.disgenet.org/resource/nanopub/NP1150743.RAmhfljqI2uB50VOgwPHD1jgWZajvpN7oLhLAIrWdiByw#assertion http://semanticscience.org/resource/SIO_000772 http://identifiers.org/pubmed/24780838 http://rdf.disgenet.org/resource/nanopub/NP1150743.RAmhfljqI2uB50VOgwPHD1jgWZajvpN7oLhLAIrWdiByw#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://rdf.disgenet.org/v5.0.0/void/BEFREE http://rdf.disgenet.org/resource/nanopub/NP1150743.RAmhfljqI2uB50VOgwPHD1jgWZajvpN7oLhLAIrWdiByw#assertion http://www.w3.org/ns/prov#wasGeneratedBy http://purl.obolibrary.org/obo/ECO_0000203 http://rdf.disgenet.org/v5.0.0/void/BEFREE http://purl.org/pav/importedOn 2017-02-19 http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://purl.obolibrary.org/obo/ECO_0000212 http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature http://www.w3.org/2000/01/rdf-schema#comment Gene-disease associations inferred from text-mining the literature. http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature http://www.w3.org/2000/01/rdf-schema#label DisGeNET evidence - LITERATURE http://rdf.disgenet.org/resource/nanopub/NP1150743.RAmhfljqI2uB50VOgwPHD1jgWZajvpN7oLhLAIrWdiByw#publicationInfo http://rdf.disgenet.org/resource/nanopub/NP1150743.RAmhfljqI2uB50VOgwPHD1jgWZajvpN7oLhLAIrWdiByw http://purl.org/dc/terms/created 2017-10-17T13:17:31+02:00 http://rdf.disgenet.org/resource/nanopub/NP1150743.RAmhfljqI2uB50VOgwPHD1jgWZajvpN7oLhLAIrWdiByw http://purl.org/dc/terms/rights http://opendatacommons.org/licenses/odbl/1.0/ http://rdf.disgenet.org/resource/nanopub/NP1150743.RAmhfljqI2uB50VOgwPHD1jgWZajvpN7oLhLAIrWdiByw http://purl.org/dc/terms/rightsHolder http://rdf.disgenet.org/v5.0.0/void/IBIGroup http://rdf.disgenet.org/resource/nanopub/NP1150743.RAmhfljqI2uB50VOgwPHD1jgWZajvpN7oLhLAIrWdiByw http://purl.org/dc/terms/subject http://semanticscience.org/resource/SIO_000983 http://rdf.disgenet.org/resource/nanopub/NP1150743.RAmhfljqI2uB50VOgwPHD1jgWZajvpN7oLhLAIrWdiByw http://purl.org/net/provenance/ns#usedData http://rdf.disgenet.org/v5.0.0/void/disgenetv3.0rdf http://rdf.disgenet.org/resource/nanopub/NP1150743.RAmhfljqI2uB50VOgwPHD1jgWZajvpN7oLhLAIrWdiByw http://purl.org/pav/authoredBy http://orcid.org/0000-0001-5999-6269 http://rdf.disgenet.org/resource/nanopub/NP1150743.RAmhfljqI2uB50VOgwPHD1jgWZajvpN7oLhLAIrWdiByw http://purl.org/pav/authoredBy http://orcid.org/0000-0002-7534-7661 http://rdf.disgenet.org/resource/nanopub/NP1150743.RAmhfljqI2uB50VOgwPHD1jgWZajvpN7oLhLAIrWdiByw http://purl.org/pav/authoredBy http://orcid.org/0000-0002-9383-528X http://rdf.disgenet.org/resource/nanopub/NP1150743.RAmhfljqI2uB50VOgwPHD1jgWZajvpN7oLhLAIrWdiByw http://purl.org/pav/authoredBy http://orcid.org/0000-0003-0169-8159 http://rdf.disgenet.org/resource/nanopub/NP1150743.RAmhfljqI2uB50VOgwPHD1jgWZajvpN7oLhLAIrWdiByw http://purl.org/pav/authoredBy http://orcid.org/0000-0003-1244-7654 http://rdf.disgenet.org/resource/nanopub/NP1150743.RAmhfljqI2uB50VOgwPHD1jgWZajvpN7oLhLAIrWdiByw http://purl.org/pav/createdBy http://orcid.org/0000-0003-0169-8159 http://rdf.disgenet.org/resource/nanopub/NP1150743.RAmhfljqI2uB50VOgwPHD1jgWZajvpN7oLhLAIrWdiByw http://purl.org/pav/version v5.0.0.0 http://rdf.disgenet.org/v5.0.0/void/disgenetv3.0rdf http://purl.org/pav/version v5.0.0