. . . . . . . "[To understand the individual and combined roles of HIF-1? and HIF-2? in cancer metabolism and oncogenic KRAS signaling, we used targeted homologous recombination to disrupt the oncogenic KRAS, HIF-1?, and HIF-2? gene loci in HCT116 colon cancer cells to generate isogenic HCT116WT KRAS, HCT116HIF-1?-/-, HCT116HIF-2?-/-, and HCT116HIF-1?-/-HIF-2?-/- cell lines.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2017-02-19"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2017-10-17T13:12:18+02:00"^^ . . . . . . . . . . . "v5.0.0.0" . "v5.0.0" .