sub:provenance {
sub:assertion dcterms:description "[Importantly, the clinical antidepressant response of patients with depression (n = 51) could be predicted by the antidepressant response of autophagic markers in patient-derived peripheral blood lymphocytes cultivated and treated ex vivo (Beclin1/amitriptyline: r = 0.572, p = 0.003; Beclin1/PAR: r = 0.569, p = 0.004; Beclin1/fluoxetine: r = 0.454, p = 0.026; pAkt/amitriptyline: r = ?-0.416, p = 0.006; pAkt/PAR: r = ?-0.355, p = 0.021; LC3B-II/PAR: r = 0.453, p = 0.02), as well as by the lymphocytic expression levels of FKBP51 (r = 0.631, p<0.0001), pAkt (r =? -0.515, p = 0.003), and Beclin1 (r = 0.521, p = 0.002) at admission.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en ;
wi:evidence dgn-void:source_evidence_curated ;
sio:SIO_000772 miriam-pubmed:25386878 ;
prov:wasDerivedFrom dgn-void:PSYGENET ;
prov:wasGeneratedBy eco:ECO_0000218 .
dgn-void:PSYGENET pav:importedOn "2017-01-25"^^
xsd:date .
dgn-void:source_evidence_curated a eco:ECO_0000205 ;
rdfs:comment "Gene-disease associations manually curated."@en ;
rdfs:label "DisGeNET evidence - CURATED"@en .
}