http://purl.org/np/RAlJU80kTj0iu2-l-oZVnqRvUtoTnh9kjQDVzFdjh5iEo#Head http://purl.org/np/RAlJU80kTj0iu2-l-oZVnqRvUtoTnh9kjQDVzFdjh5iEo http://www.nanopub.org/nschema#hasAssertion http://purl.org/np/RAlJU80kTj0iu2-l-oZVnqRvUtoTnh9kjQDVzFdjh5iEo#assertion http://purl.org/np/RAlJU80kTj0iu2-l-oZVnqRvUtoTnh9kjQDVzFdjh5iEo http://www.nanopub.org/nschema#hasProvenance http://purl.org/np/RAlJU80kTj0iu2-l-oZVnqRvUtoTnh9kjQDVzFdjh5iEo#provenance http://purl.org/np/RAlJU80kTj0iu2-l-oZVnqRvUtoTnh9kjQDVzFdjh5iEo http://www.nanopub.org/nschema#hasPublicationInfo http://purl.org/np/RAlJU80kTj0iu2-l-oZVnqRvUtoTnh9kjQDVzFdjh5iEo#pubInfo http://purl.org/np/RAlJU80kTj0iu2-l-oZVnqRvUtoTnh9kjQDVzFdjh5iEo http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://purl.org/np/RAlJU80kTj0iu2-l-oZVnqRvUtoTnh9kjQDVzFdjh5iEo#assertion http://purl.org/np/RAlJU80kTj0iu2-l-oZVnqRvUtoTnh9kjQDVzFdjh5iEo#assertion http://www.w3.org/ns/prov#wasGeneratedBy S&T TWOC project version 1 http://purl.org/np/RAlJU80kTj0iu2-l-oZVnqRvUtoTnh9kjQDVzFdjh5iEo#version http://www.w3.org/ns/prov#value 1 http://www.w3.org/1999/02/22-rdf-syntax-ns#object https://uts.nlm.nih.gov/uts/umls/concept/C0018787 heart http://www.w3.org/1999/02/22-rdf-syntax-ns#object https://uts.nlm.nih.gov/uts/umls/concept/C0026691 Kawasaki disease http://www.w3.org/1999/02/22-rdf-syntax-ns#object https://uts.nlm.nih.gov/uts/umls/concept/C0027552 need http://www.w3.org/1999/02/22-rdf-syntax-ns#object https://uts.nlm.nih.gov/uts/umls/concept/C0039082 syndrome http://www.w3.org/1999/02/22-rdf-syntax-ns#object https://uts.nlm.nih.gov/uts/umls/concept/C0162340 understand http://www.w3.org/1999/02/22-rdf-syntax-ns#object https://uts.nlm.nih.gov/uts/umls/concept/C0205082 severe http://www.w3.org/1999/02/22-rdf-syntax-ns#object https://uts.nlm.nih.gov/uts/umls/concept/C0524637 recognition http://www.w3.org/1999/02/22-rdf-syntax-ns#object https://uts.nlm.nih.gov/uts/umls/concept/C0699748 pathogenesis http://www.w3.org/1999/02/22-rdf-syntax-ns#object https://uts.nlm.nih.gov/uts/umls/concept/C1279919 early http://www.w3.org/1999/02/22-rdf-syntax-ns#object https://uts.nlm.nih.gov/uts/umls/concept/C1281570 heart http://www.w3.org/1999/02/22-rdf-syntax-ns#object https://uts.nlm.nih.gov/uts/umls/concept/C1519275 severe http://www.w3.org/1999/02/22-rdf-syntax-ns#object https://uts.nlm.nih.gov/uts/umls/concept/C1547227 severe http://www.w3.org/1999/02/22-rdf-syntax-ns#object https://uts.nlm.nih.gov/uts/umls/concept/C1547231 severe http://www.w3.org/1999/02/22-rdf-syntax-ns#object https://uts.nlm.nih.gov/uts/umls/concept/C1561581 severe http://www.w3.org/1999/02/22-rdf-syntax-ns#object https://uts.nlm.nih.gov/uts/umls/concept/C2362545 urgent care http://www.w3.org/1999/02/22-rdf-syntax-ns#object https://uts.nlm.nih.gov/uts/umls/concept/C4050465 severe http://www.w3.org/1999/02/22-rdf-syntax-ns#object https://uts.nlm.nih.gov/uts/umls/concept/C4050466 severe http://www.w3.org/1999/02/22-rdf-syntax-ns#object https://uts.nlm.nih.gov/uts/umls/concept/C4722466 severe http://www.w3.org/1999/02/22-rdf-syntax-ns#object https://uts.nlm.nih.gov/uts/umls/concept/C4761449 severe http://www.w3.org/1999/02/22-rdf-syntax-ns#object https://uts.nlm.nih.gov/uts/umls/concept/C5203119 severe http://www.w3.org/1999/02/22-rdf-syntax-ns#object https://uts.nlm.nih.gov/uts/umls/concept/C5238705 syndrome http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://twoc-nlp-database-server-1:8555/solr/predicates/select?q=TRIPLE_UID:zwws4ij3-TRIPLE-ABSTRACT-14 need http://www.w3.org/1999/02/22-rdf-syntax-ns#subject https://uts.nlm.nih.gov/uts/umls/concept/C0011777 dexamethasone http://www.w3.org/1999/02/22-rdf-syntax-ns#subject https://uts.nlm.nih.gov/uts/umls/concept/C0025815 methylprednisolone http://www.w3.org/1999/02/22-rdf-syntax-ns#subject https://uts.nlm.nih.gov/uts/umls/concept/C0035168 research http://www.w3.org/1999/02/22-rdf-syntax-ns#subject https://uts.nlm.nih.gov/uts/umls/concept/C0242481 research http://www.w3.org/1999/02/22-rdf-syntax-ns#subject https://uts.nlm.nih.gov/uts/umls/concept/C1517331 Further http://www.w3.org/1999/02/22-rdf-syntax-ns#subject https://uts.nlm.nih.gov/uts/umls/concept/C1548287 research http://www.w3.org/1999/02/22-rdf-syntax-ns#subject https://uts.nlm.nih.gov/uts/umls/concept/C3245477 research http://www.w3.org/2000/01/rdf-schema#Triple-UID http://twoc-nlp-database-server-1:8555/solr/triples/select?q=TRIPLE_UID:zwws4ij3-TRIPLE-ABSTRACT-14 zwws4ij3-TRIPLE-ABSTRACT-14 http://www.w3.org/2000/01/rdf-schema#sentence http://www.w3.org/2000/01/rdf-schema#label During the COVD-19 pandemic, some pediatric patients in many countries around the world experienced a syndrome resembling a severe Kawasaki disease (KD), often accompanied by shock Due to the incomplete signs of a severe Kawasaki disease (KD) in the era before the COVD-19 pandemic, in many publications from European countries and the United States, this condition was called «multisystem inflammatory syndrome in children – MIS-C» or «hyperinflammatory shock» or «Kawasaki-like syndrome» this condition is characterized by refractory fever, frequent gastrointestinal symptoms, heart damage (including coronary dilation in some patients, and acute left ventricular failure in the majority), increased ESR and CRP levels, neutrophilia, extremely high troponin levels, increased ferritin, AST, ALT, lactate dehydrogenase, creatine phosphate kinase, interleukin-6 and interleukin-10, coagulopathy with an increase in D-dimer and fibrinogen, thrombocytopenia, sometimes procalcitonin increase The manifestations of a cytokine storm may meet the criteria for secondary hemophagocytic syndrome The mechanism of myocardial damage remains unclear Treatment with high-dose intravenous immunoglobulin is effective, and in the presence of signs of hemophagocytic syndrome, dexamethasone or methylprednisolone Further research is needed to understand the pathogenesis, resemblance and differences of this syndrome with a severe Kawasaki disease (KD), understanding of heart injuiry and early recognition for the need of urgent care http://www.w3.org/2000/01/rdf-schema#triple http://www.w3.org/2000/01/rdf-schema#label dexamethasone or methylprednisolone Further research needed to understand the pathogenesis , resemblance and differences of this syndrome with a severe Kawasaki disease ( KD ) , understanding of heart injuiry and early recognition for the need of urgent care http://purl.org/np/RAlJU80kTj0iu2-l-oZVnqRvUtoTnh9kjQDVzFdjh5iEo#provenance http://purl.org/np/RAlJU80kTj0iu2-l-oZVnqRvUtoTnh9kjQDVzFdjh5iEo#assertion http://www.w3.org/ns/prov#generatedAtTime 2021-07-25T21:46:58.429988 http://purl.org/np/RAlJU80kTj0iu2-l-oZVnqRvUtoTnh9kjQDVzFdjh5iEo#pubInfo http://purl.org/np/RAlJU80kTj0iu2-l-oZVnqRvUtoTnh9kjQDVzFdjh5iEo#sig http://purl.org/nanopub/x/hasAlgorithm RSA http://purl.org/np/RAlJU80kTj0iu2-l-oZVnqRvUtoTnh9kjQDVzFdjh5iEo#sig http://purl.org/nanopub/x/hasPublicKey MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCSLeezU8JYlBsrgXOGXX4fxOq4oydsMzMK1CN0Rez2OEd2IYk18R4DetcZXwGhN3Pil7qcgNkiGvTirJXIo8zHl7jVehs19EdYtrttCKEaXRzWIr4LuCrfGedkvonEMWqR8e1GdQsLgEEyM50BD6Qw+srQt9ozcqf/9wG2MAMX9QIDAQAB http://purl.org/np/RAlJU80kTj0iu2-l-oZVnqRvUtoTnh9kjQDVzFdjh5iEo#sig http://purl.org/nanopub/x/hasSignature P3egr1nL2cVWZDCv6XkDzfuclqTN+zTG0/FFQ2TMyTHU0OgEDIQ2pINhYsawzesgN4Bes0/kWi+7LYyJ8F889tQjy5BmbwN0TcOynKLbUcRXDnAw7tGDctXiD0rn5V8t3DrEi75iHUgC239u90mCESbt9QV1F9eB1WUZbwFgKY0= http://purl.org/np/RAlJU80kTj0iu2-l-oZVnqRvUtoTnh9kjQDVzFdjh5iEo#sig http://purl.org/nanopub/x/hasSignatureTarget http://purl.org/np/RAlJU80kTj0iu2-l-oZVnqRvUtoTnh9kjQDVzFdjh5iEo http://purl.org/np/RAlJU80kTj0iu2-l-oZVnqRvUtoTnh9kjQDVzFdjh5iEo http://www.w3.org/ns/prov#generatedAtTime 2021-07-25T21:46:58.429988 http://purl.org/np/RAlJU80kTj0iu2-l-oZVnqRvUtoTnh9kjQDVzFdjh5iEo http://www.w3.org/ns/prov#wasAttributedTo https://orcid.org/0000-0002-8954-0470