@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix ns1: <http://www.w3.org/ns/prov#> .
@prefix this: <http://purl.org/np/RAkIkrZ6Asi5iRRgsmOUe2er4vDeHCiiddAO4lBikAxbQ> .
@prefix sub: <http://purl.org/np/RAkIkrZ6Asi5iRRgsmOUe2er4vDeHCiiddAO4lBikAxbQ#> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix nt: <https://w3id.org/np/o/ntemplate/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix orcid: <https://orcid.org/> .
@prefix bl: <https://w3id.org/biolink/vocab/> .
@prefix nkg: <https://w3id.org/um/neurodkg/> .
@prefix npx: <http://purl.org/nanopub/x/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo;
    a np:Nanopublication .
}

sub:assertion {
  <http://purl.obolibrary.org/obo/MONDO_0021146> bl:category bl:Disease .
  
  sub:association rdf:object <http://purl.obolibrary.org/obo/MONDO_0021146>;
    rdf:predicate bl:treats;
    rdf:subject <https://go.drugbank.com/drugs/DB00321>;
    a rdf:Statement;
    rdfs:label "TCAs have been shown to be effective for managing and preventing chronic headache syndromes.3,4";
    bl:association_type bl:ChemicalToDiseaseOrPhenotypicFeatureAssociation;
    bl:has_population_context sub:cohort;
    bl:provided_by <https://w3id.org/um/NeuroDKG>;
    bl:publications <https://pubmed.ncbi.nlm.nih.gov/31821138>;
    bl:relation nkg:OffLabelIndication .
  
  sub:cohort rdfs:label "Adults";
    bl:category bl:Cohort .
  
  <https://go.drugbank.com/drugs/DB00321> bl:category bl:Drug .
}

sub:provenance {
  sub:assertion ns1:wasAttributedTo orcid:0000-0002-7641-6446 .
}

sub:pubinfo {
  sub:sig npx:hasAlgorithm "RSA";
    npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCamPJb4SzqpLXn//XJ5dlVfzz6QI+RPmiJTLXF/by2JR7sHMKRsCQDFsYMlq8zGHghOIkjRP9dpLZUtZzUcHt3MXiFKEPo8eGzUe9p+JXKFC8xxkJr94z2vq6IdMf71Iu1GH8SeDAKt/DgYO4zNaw8VuXvxnZRewKZSA+u8zWPVwIDAQAB";
    npx:hasSignature "CTtI7PGj5w143Dr+uS6++9HdTasSFl1ipH1aGQ3yWF9KxNYkQhrg7s0r6yLgV5qgQ2y8QPULa6IDfxUaIHQxJTteIzaUhzvQnkPzPrP/Yv0goEqj95BcyklOFyt2ZY7J4vG5NmFtNDfn/a14oDrJb/aaAhpJ1q6ncpePTlGoBVM=";
    npx:hasSignatureTarget this: .
  
  this: dcterms:created "2021-06-28T18:01:46.567+02:00"^^xsd:dateTime;
    dcterms:creator orcid:0000-0002-7641-6446;
    nt:wasCreatedFromProvenanceTemplate <http://purl.org/np/RANwQa4ICWS5SOjw7gp99nBpXBasapwtZF1fIM3H2gYTM>;
    nt:wasCreatedFromPubinfoTemplate <http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM>;
    nt:wasCreatedFromTemplate <http://purl.org/np/RAManV5GZI01JKzW_IPcfOXoiFTcZMmsV7qTCLkdzr4Gs> .
}