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[The higher expressions of PPAR? and NF-?B in ICP placenta and TCA treated HTR-8/SVneo cell, together with the abnormal serum levels of cytokines, might induced by the imbalance of inflammatory and immune reaction, and then disturb placental bile acid and serum lipids transportation, finally result in fatal cholestasis which probably be one of the mechanism of ICP.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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