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[Toll-like receptor 4 (TLR4) represents a reasonable functional and positional candidate gene for Alzheimer's disease (AD) as it is located within the previous identified linkage region of AD on chromosome 9q, and functionally is involved in the microglia-mediated inflammatory response, amyloid-? (A?) plaque formation and A? clearance.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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