@prefix bl: <https://w3id.org/biolink/vocab/> .
@prefix nkg: <https://w3id.org/um/neurodkg/> .
@prefix nt: <https://w3id.org/np/o/ntemplate/> .
@prefix orcid: <https://orcid.org/> .
@prefix this: <http://purl.org/np/RAivaI9R59azEQYT7xfZPxx8AtXSjgWxIXjuLQbmDvImY> .
@prefix sub: <http://purl.org/np/RAivaI9R59azEQYT7xfZPxx8AtXSjgWxIXjuLQbmDvImY#> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubInfo;
    a np:Nanopublication .
}

sub:assertion {
  <http://purl.obolibrary.org/obo/MONDO_0004985> a bl:Disease .
  
  sub:association rdf:object <http://purl.obolibrary.org/obo/MONDO_0004985>;
    rdf:predicate bl:treats;
    rdf:subject <https://identifiers.org/DRUGBANK:DB00363>;
    a rdf:Statement;
    rdfs:label "Moreover, although the studies were uncontrolled, a significant body of literature has highlighted the potential benefit of clozapine in the treatment of acute mania, the depressive phase of BD, and in overall mood stabilization, with some evidence suggesting its use not only in treatment-resistant schizophrenia but also in treatment-refractory BD.";
    bl:has_population_context sub:context;
    bl:provided_by <https://w3id.org/um/NeuroDKG>;
    bl:publications <https://pubmed.ncbi.nlm.nih.gov/31291215>;
    bl:relation nkg:OffLabelIndication .
  
  sub:context a bl:Cohort;
    rdfs:label "Adults" .
  
  <https://identifiers.org/DRUGBANK:DB00363> a bl:Drug .
}

sub:provenance {
  sub:assertion prov:generatedAtTime "2021-08-17T13:35:42.767360"^^xsd:dateTime .
}

sub:pubInfo {
  sub:sig npx:hasAlgorithm "RSA";
    npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCamPJb4SzqpLXn//XJ5dlVfzz6QI+RPmiJTLXF/by2JR7sHMKRsCQDFsYMlq8zGHghOIkjRP9dpLZUtZzUcHt3MXiFKEPo8eGzUe9p+JXKFC8xxkJr94z2vq6IdMf71Iu1GH8SeDAKt/DgYO4zNaw8VuXvxnZRewKZSA+u8zWPVwIDAQAB";
    npx:hasSignature "a+I1JioXRQmxBRBrgIgPVOSzqnO836obXdtaqToCx0qB/2g26ftsY7dqWFeGDHubiPoJs/a44m8vIkZYu+Vk36oRwduM3hoF/tsI3qAKJoA08hiRHDc59lqs4rZOWdg1wvgzV9z8ZeDFDmLjWYAct7bavzqveskXL2PcTlRroLw=";
    npx:hasSignatureTarget this: .
  
  this: prov:generatedAtTime "2021-08-17T13:35:42.767360"^^xsd:dateTime;
    prov:wasAttributedTo orcid:0000-0002-7641-6446;
    nt:wasCreatedFromTemplate <http://purl.org/np/RAhNHZw6Urw_Mccs4qy6Ws3C9CRuaHpQx8AwuApbWkqnY> .
}