. . . . . . . "[Indeed, studies in human IBD tissues and murine models of colitis have documented a disruption of TGF-?1 signalling marked by a block in the phosphorylation of Smad3, a signalling molecule associated with the activated TGF-? receptor, due to up-regulation of Smad7, an intracellular inhibitor of Smad3 phosphorylation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2017-02-19"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2017-10-17T13:14:24+02:00"^^ . . . . . . . . . . . "v5.0.0.0" . "v5.0.0" .