. . . . . . . "[Genomic and proteomic analyses revealed that lapatinib-resistant breast cancer cells gained additional phosphoinositide 3-kinase (PI3K) activation through activating mutation in PI3K p110? and/or increasing protein expression of existing mutant p110?. p110? protein upregulation in lapatinib-resistant cells occurred through gene amplification or posttranscriptional upregulation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2017-02-19"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2017-10-17T13:15:22+02:00"^^ . . . . . . . . . . . "v5.0.0.0" . "v5.0.0" .