. . . . . . . "[' Based on clinical observations, we hypothesized that NLPR3 activation and IL-1? production, in particular in mast cells (MCs), are important for the development of this eruption, due to the observation that CAPS patients have gain-of-function mutations in NLRP3 that result in unregulated excess levels of IL-1?.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2017-02-19"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2017-10-17T13:13:44+02:00"^^ . . . . . . . . . . . "v5.0.0.0" . "v5.0.0" .