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[Among these 52 genes, 7 were related to immunity, 3 were related to the tumor necrosis factor (TNF)-? receptor 1 (TNFR1) pathway (inhibitor of caspase-activated DNase (ICAD): FC?=?1.8, P?=?1.7E-7, FDR?=?0.004; p21 protein-activated kinase 2 [PAK2]: FC?=?1.66, P?=?2.6E-5, FDR?=?0.03; TNF-?-induced protein 8-like protein 1 [TNFAIP8L1]: P?=?1.00E-05, FDR?=?0.026), and 2 were related to Toll-like receptors (TLRs), especially TLRs 7 and 9, and were implicated in autoimmunity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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DisGeNET evidence - LITERATURE
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