. . . . . . . "[Because the expression of normally silenced fetal ?-type globin genes and resultant production of fetal hemoglobin (HbF) in adult erythroid cells can ameliorate the pathophysiological consequences of both abnormal ?-globin chains in sickle cell anemia and deficient ?-globin chain production in ?-thalassemia, understanding the complex mechanisms of this developmental switch has direct translational clinical relevance.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2017-02-19"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2017-10-17T13:13:13+02:00"^^ . . . . . . . . . . . "v5.0.0.0" . "v5.0.0" .