. . . . . . . "[We propose that MAFA, MAFB, NKX6.1, and PDX1 activity provides a gauge of islet ? cell function, with loss of MAFA (and/or MAFB) representing an early indicator of ? cell inactivity and the subsequent deficit of more impactful NKX6.1 (and/or PDX1) resulting in overt dysfunction associated with T2DM.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2017-02-19"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2017-10-17T13:14:00+02:00"^^ . . . . . . . . . . . "v5.0.0.0" . "v5.0.0" .