. . . . . . . "[More importantly, persistent activation of Wnt signaling through Wnt ligands, or inhibition of negative regulators of Wnt signaling, such as Dickkopf-1 (DKK-1) and glycogen synthase kinase-3 ? (GSK-3 ? ) that are hyperactive in the disease state, is able to protect against A ? toxicity and ameliorate cognitive performance in AD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2017-02-19"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2017-10-17T13:13:06+02:00"^^ . . . . . . . . . . . "v5.0.0.0" . "v5.0.0" .