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[This work reports the first evidence that 15dPGJ2 treatment increases the number of intracellular parasites as shown by fluorescence microscopy and it is also able to inhibit the expression and activity of different inflammatory enzymes such as inducible nitric oxide synthase (NOS-2), matrix metalloproteinases 2 and 9 (MMP-2, MMP-9), as well as pro-inflammatory cytokine (TNF-? and IL-6) mRNA expression in neonatal mouse cardiomyocytes after T. cruzi infection.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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