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[Proinflammatory and bronchoconstrictive actions of adenosine in the asthmatic lung are well recognized, with the latter being mediated, in part, through A(1) receptor activation on airway smooth muscle.In this issue of the JCI, Sun et al. report findings in adenosine deaminase-deficient mice that suggest the occurrence of anti-inflammatory actions of adenosine in the lung, mediated through A(1) adenosine receptors on macrophages.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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