. . . . . . . "[In contrast, pathogenesis of other chronic lung diseases like ?F508-cystic fibrosis (CF), ?1-anti-trypsin-deficiency (?-1 ATD) and pulmonary fibrosis (PF) is regulated by other proteostatic mechanisms, involving the degradation of misfolded proteins (?F508-CFTR/?1-AT- Z variant) or regulating the concentration of signaling proteins (such as TGF-?1) by the ubiquitin-proteasome system (UPS).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2017-02-19"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2017-10-17T13:16:39+02:00"^^ . . . . . . . . . . . "v5.0.0.0" . "v5.0.0" .