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[To test the role of inflammation severity in stem cell-mediated tissue repair, we employed mice with carbon tetrachloride-induced advanced liver fibrosis and found that although MSCs alone were effective, concurrent administration of Dex abrogated the therapeutic effects of MSCs on fibrin deposition, serum levels of bilirubin, albumin, and aminotransferases, as well as T-lymphocyte infiltration, especially IFN-?(+)CD4(+) and IL-17A(+)CD4(+)T cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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