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[Inflammatory cell and cytokine profile (nuclear factor-?B, IL-6, tumor necrosis factor-?), intracellular polymerization of Z-AT, and endoplasmic reticulum (ER) stress markers (protein kinase RNA-like ER kinase, activator transcription factor 4) were assessed in transgenic mice and transfected cells in response to cigarette smoke, and in explanted lungs from ZZ and MM individuals with severe COPD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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