@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix ns1: <http://www.w3.org/ns/prov#> .
@prefix this: <http://purl.org/np/RANzNgKy0eZSMRBce-sA0BUEc1Af4S_h-EK011_sMdn_w> .
@prefix sub: <http://purl.org/np/RANzNgKy0eZSMRBce-sA0BUEc1Af4S_h-EK011_sMdn_w#> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix nt: <https://w3id.org/np/o/ntemplate/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix orcid: <https://orcid.org/> .
@prefix bl: <https://w3id.org/biolink/vocab/> .
@prefix nkg: <https://w3id.org/um/neurodkg/> .
@prefix npx: <http://purl.org/nanopub/x/> .
sub:Head {
  this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubinfo ;
    a np:Nanopublication .
}
sub:assertion {
  <http://purl.obolibrary.org/obo/MONDO_0005052> bl:category bl:Disease .
  sub:association rdf:object <http://purl.obolibrary.org/obo/MONDO_0005052> ;
    rdf:predicate bl:treats ;
    rdf:subject <https://go.drugbank.com/drugs/DB00321> ;
    a rdf:Statement ;
    rdfs:label "Patients with irritable bowel syndrome have long been known to benefit from TCAs; the number needed to treat for symptomatic benefit over placebo is 3.5" ;
    bl:association_type bl:ChemicalToDiseaseOrPhenotypicFeatureAssociation ;
    bl:has_population_context sub:cohort ;
    bl:provided_by <https://w3id.org/um/NeuroDKG> ;
    bl:publications <https://pubmed.ncbi.nlm.nih.gov/31821138> ;
    bl:relation nkg:OffLabelIndication .
  sub:cohort rdfs:label "Adults" ;
    bl:category bl:Cohort .
  <https://go.drugbank.com/drugs/DB00321> bl:category bl:Drug .
}
sub:provenance {
  sub:assertion ns1:wasAttributedTo orcid:0000-0002-7641-6446 .
}
sub:pubinfo {
  sub:sig npx:hasAlgorithm "RSA" ;
    npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCamPJb4SzqpLXn//XJ5dlVfzz6QI+RPmiJTLXF/by2JR7sHMKRsCQDFsYMlq8zGHghOIkjRP9dpLZUtZzUcHt3MXiFKEPo8eGzUe9p+JXKFC8xxkJr94z2vq6IdMf71Iu1GH8SeDAKt/DgYO4zNaw8VuXvxnZRewKZSA+u8zWPVwIDAQAB" ;
    npx:hasSignature "GDYvaigUu4U+aR2bquL4GhTmOeDU0W4GWo7af0Y+j+3am02iaz78y2cJ+x3Wh2bRGEW71ClgjgOv5YvmN8ajBRU4K3q/heMn82eBkzMCbvQBzpaLZJZPANlqXtZmr2WLPPhj/5Wxi/PAHlArL9ufMjTjKEfJhvSotY5jA4t43MQ=" ;
    npx:hasSignatureTarget this: .
  this: dcterms:created "2021-06-28T19:56:14.152+02:00"^^xsd:dateTime ;
    dcterms:creator orcid:0000-0002-7641-6446 ;
    nt:wasCreatedFromProvenanceTemplate <http://purl.org/np/RANwQa4ICWS5SOjw7gp99nBpXBasapwtZF1fIM3H2gYTM> ;
    nt:wasCreatedFromPubinfoTemplate <http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM> ;
    nt:wasCreatedFromTemplate <http://purl.org/np/RAManV5GZI01JKzW_IPcfOXoiFTcZMmsV7qTCLkdzr4Gs> .
}