@prefix nkg: <https://w3id.org/um/neurodkg/> .
@prefix nt: <https://w3id.org/np/o/ntemplate/> .
@prefix orcid: <https://orcid.org/> .
@prefix bl: <https://w3id.org/biolink/vocab/> .
@prefix this: <http://purl.org/np/RAJbVIE1fMI-rcUYoOQzrlcUkOLkb7N6UxKCpor8ueX9s> .
@prefix sub: <http://purl.org/np/RAJbVIE1fMI-rcUYoOQzrlcUkOLkb7N6UxKCpor8ueX9s#> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubInfo;
    a np:Nanopublication .
}

sub:assertion {
  <http://purl.obolibrary.org/obo/HP_0000737> a bl:Disease .
  
  sub:association rdf:object <http://purl.obolibrary.org/obo/HP_0000737>;
    rdf:predicate bl:treats;
    rdf:subject <https://identifiers.org/DRUGBANK:DB01267>;
    a rdf:Statement;
    rdfs:label "Fernandez-Mayoralas et al. [12] have conducted a prospective 16-week open-label study of paliperidone in 18 patients (mean age, 13.4 years) with severe and excessive irritability in the context of generalized developmental disorders or ADHD.";
    bl:has_population_context sub:context;
    bl:provided_by <https://w3id.org/um/NeuroDKG>;
    bl:publications <https://pubmed.ncbi.nlm.nih.gov/31096228>;
    bl:relation nkg:OffLabelIndication .
  
  sub:context a bl:Cohort;
    rdfs:label "Children and adolescents (mean age 13.4 years)";
    bl:has_phenotype <http://purl.obolibrary.org/obo/MONDO_0007743> .
  
  <https://identifiers.org/DRUGBANK:DB01267> a bl:Drug .
}

sub:provenance {
  sub:assertion prov:generatedAtTime "2021-08-24T15:54:02.096714"^^xsd:dateTime .
}

sub:pubInfo {
  sub:sig npx:hasAlgorithm "RSA";
    npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCamPJb4SzqpLXn//XJ5dlVfzz6QI+RPmiJTLXF/by2JR7sHMKRsCQDFsYMlq8zGHghOIkjRP9dpLZUtZzUcHt3MXiFKEPo8eGzUe9p+JXKFC8xxkJr94z2vq6IdMf71Iu1GH8SeDAKt/DgYO4zNaw8VuXvxnZRewKZSA+u8zWPVwIDAQAB";
    npx:hasSignature "Ua9E8ETK4X2u5KEkco3yp/6pUk+2sNfQ/0rTMgCFxI22oZpLxro77v/jm52L2ju8Lv+cGFvaYK1oHt2p8jJqYmxBf6fcTyXBJI10SEaG993gCUM9TJoNjzyDpqNFaW2C4DtdVmW0ASZ/jqOTyiqsLr42cOeMSQwn2xvBYN+gGEQ=";
    npx:hasSignatureTarget this: .
  
  this: prov:generatedAtTime "2021-08-24T15:54:02.096714"^^xsd:dateTime;
    prov:wasAttributedTo orcid:0000-0002-7641-6446;
    nt:wasCreatedFromTemplate <http://purl.org/np/RAhNHZw6Urw_Mccs4qy6Ws3C9CRuaHpQx8AwuApbWkqnY> .
}