. . . . . . . "[These findings suggest that the first step toward cyst formation in PKD1 patients is the loss of one functional copy of polycystin 1, which indirectly supports the 'two-hit' model of cystogenesis where a second somatic mutation inactivating the normal allele is necessary to occur for development of the disease condition.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2017-02-19"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2017-10-17T13:15:26+02:00"^^ . . . . . . . . . . . "v5.0.0.0" . "v5.0.0" .